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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Zinc plays a crucial role in neurotransmission, synaptic plasticity, and neurogenesis. Zinc deficiency has been associated with attentional deficits in children and diminished executive functioning in older adults. However, the association between serum zinc and cognitive performance in patients with kidney failure undergoing maintenance hemodialysis remains unclear, although zinc deficiency is highly prevalent in this population. This study aimed to examine the association between serum zinc and cognitive function in patients undergoing maintenance hemodialysis.
In this cross-sectional study, 1207 eligible patients were selected. Cognitive function was assessed by using the Modified Mini-Mental State examination (3MS). The association between serum zinc and 3MS total score was examined by using a linear regression model. The associations between serum zinc and the eight cognitive domains of 3MS were further examined using ordinal logistic regression model.
In total patients, 3MS score and serum zinc levels were 91 (82-97) points and 68 (61-76) μg/dL, respectively. Serum zinc level was positively associated with 3MS score in unadjusted model (p=0.006). However, the association was no longer significant in adjusted model with 17 potential confounders including serum albumin levels (p=0.794). Because there was a close correlation between serum zinc and albumin levels, we conducted further analyses in which participants were categorized into 2 subgroups by the median serum albumin level (3.7 g/dL). In the lower serum albumin group (N=445), the positive association between serum zinc and 3MS was significant after adjustment for 16 potential confounders (p=0.049). Among the cognitive domains of the 3MS, attention and long-term memory were significantly associated with serum zinc levels in participants with lower serum albumin group, even after adjusted for 16 potential confounders (p=0.013 and 0.049, respectively).
Lower serum zinc was associated with lower cognitive function, especially in attention and long-term memory, in patients undergoing maintenance hemodialysis with lower serum albumin level.
