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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
The neutrophil-to-lymphocyte ratio (NLR) is a recognized indicator of systemic inflammation and a predictor of mortality in conditions such as cancer and cardiovascular disease. In the context of chronic kidney disease, an elevated NLR has been identified as a marker of mortality in patients on hemodialysis and as an independent risk factor for disease progression. Another hematological parameter, the platelet-to-lymphocyte ratio (PLR), has been less extensively studied than the NLR. Although early post-transplant inflammation is a known predictor of long-term mortality, the utility of NLR or PLR as a specific predictors of delayed graft function (DGF) is not well established. This study therefore aimed to characterize the two-year temporal trajectories of NLR and PLR in kidney transplant (KT) recipients and to assess their association with the incidence of DGF.
This was a retrospective single-center cohort study including all patients who underwent KT between 2020 and 2022. From an initial cohort of 60 patients, eight were excluded due to all-cause mortality within the two-year follow-up period, resulting in a final study population of 52 patients. Logistic regression analysis was performed to evaluate the association between pre-transplant (month zero) NLR and PLR and the occurrence of DGF.
The cohort consisted predominantly of middle-aged (49.9 ± 12.4 years), most of whom were white (73.2%) and female (55.8%), with a high prevalence of hypertension (80.8%) and diabetes (28.8%). All transplants were from deceased donors, and the incidence of DGF was 35.3%. Pre-transplant inflammatory markers showed a median NLR of 3.4 (IQR 2.1 – 4.3) and a PLR of 135.7 (IQR 107.7 – 172.3). The incidence of acute rejection was low (7.7%), whereas cytomegalovirus infection occurred in approximately half of the patients (51.9%). Over the two-year follow-up, both NLR and PLR exhibited an early posttransplant peak within the first month, followed by a gradual decline during the first trimester. Thereafter, a mild downward trend was observed, with increased variability at later time points, suggesting heterogeneous long-term inflammatory responses. In logistic regression analysis, NLR showed no association with DGF (OR = 1.02; 95% CI 0.83-1.25, p = 0.87), with stable predicted probabilities across all NLR values. In contrast, PLR exhibited a positive, though borderline, association with DGF risk (OR = 1.01; 95% CI 0.99-1.02,p=0.06).p=0.06).
Both NLR and PLR showed a transient early increase followed by gradual decline and greater variability over time. Although not statistically significant, the PLR suggests potential biological relevance and may represent a more sensitive inflammatory marker for DGF.
