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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Living donor nephrectomy is a surgery with low complication rate. However, donor long-term renal functional reserve and risk of post-donation chronic kidney disease (CKD) remain areas of active investigation, with limited data from Asian populations. This retrospective cohort study examined post-operative CKD development and associated risk factors among donor nephrectomy patients in Hong Kong over 15 years.
We analyzed all living kidney donors from all four Hong Kong renal transplant centres (2010-2024). Primary outcome was CKD development defined as final follow-up eGFR <60 mL/min/1.73m². Secondary outcomes included risk factor identification for development of post-operative CKD. Key variables examined included demographics, past health and operative data. Time to development of CKD was also analyzed.
A total of 193 patients were recruited in the study. After excluding patients with pre-operative eGFR <90 mL/min/1.73m², 153 donors were included. Mean follow-up duration was 6.6±4.2 years. Study population was predominantly female (68.0%) and Chinese (98.0%), with mean age 43.8±10.7 years and pre-operative eGFR 105.7±10.2 mL/min/1.73m². Laparoscopic nephrectomy was performed in 90.2% of cases. Primary outcome (eGFR <60) occurred in 21 patients (13.7%). At final follow-up, GFR stage distribution of Stage 1, Stage 2 and Stage 3a were 19.6%, 66.7% and 13.7% respectively, with no patients progressing to advanced stages. Significant risk factors for CKD development included: age ≥50 years (OR=5.33, 95%CI:1.99-14.28, p<0.001), male gender (OR=2.72, 95%CI:1.07-6.94, p=0.043). Pre-operative eGFR ≥100 mL/min/1.73m² was protective (OR=0.10, 95%CI:0.04-0.28, p<0.001). No patients with pre-operative eGFR ≥110 developed CKD. Kaplan-Meier analysis revealed most eGFR <60 events occurred within 6 months post-operatively, with median time of 3.0 months and mean time of 8.6±24.6 months.
Among donors with normal pre-operative kidney function, some patients developed CKD within 6 months post-operatively and no patient progressed to end stage renal failure in the cohort. Age ≥50 years and male gender emerged as significant risk factors for post-operative renal impairment, while higher pre-operative eGFR was protective. These findings support age-stratified donor selection and enhanced monitoring protocols for older donors, even those with optimal baseline function.
