ABDOMINAL AORTIC ANEURYSM IN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE UNDERGOING COMPLEX VASCULAR MALFORMATION RECONSTRUCTION – A CASE REPORT

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Abstract Title *

ABDOMINAL AORTIC ANEURYSM IN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE UNDERGOING COMPLEX VASCULAR MALFORMATION RECONSTRUCTION – A CASE REPORT

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Co-author 1

Stephanie Susantyo stephaniesusantyo@gmail.com InaSN Internal Medicine Hasanuddin University Makassar Indonesia *

Co-author 2

Haerani Rasyid haeraniabdurasyid@yahoo.com InaSN Internal Medicine Hasanuddin University Makassar Indonesia -

Co-author 3

Syakib Bakri syakib.bakri@yahoo.com InaSN Internal Medicine Hasanuddin University Makassar Indonesia -

Co-author 4

Hasyim Kasim Hasyimkasim@yahoo.com InaSN Internal Medicine Hasanuddin University Makassar Indonesia -

Co-author 5

Sitti Rabiul Zatalia Ramadhan zatalia_ramadhan@yahoo.com InaSN Internal Medicine Hasanuddin University Makassar Indonesia -

Co-author 6

Akhyar Albaar rvpakhyarmd@gmail.com InaSN Internal Medicine Hasanuddin University Makassar Indonesia -

Co-author 7

Nasrum Machmud nasrummachmud29@yahoo.com InaSN Internal Medicine Hasanuddin University Makassar Indonesia -

Co-author 8

Khadijah Khairunnisa ijhasho@gmail.com InaSN Internal Medicine Hasanuddin University Makassar Indonesia -

Co-author 9

Achmad Fikry fikryfaridin24@gmail.com InaSN Internal Medicine Hasanuddin University Makassar Indonesia -

Co-author 10

Jayarasti Kusumanegara jayarasti@gmail.com IATCVS Thoracic, Cardiac and Vascular Department Makassar Indonesia -

Co-author 11

Co-author 12

Co-author 13

Co-author 14

Co-author 15

Introduction

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a hereditary kidney disease characterized by the formation of multiple cysts and gradual progression to chronic kidney disease (CKD). In addition to renal manifestations, ADPKD also carries systemic vascular risks due to polycystin-1 and polycystin-2 dysfunction in smooth muscle and vascular endothelium, leading to arterial wall weakness and aneurysm formation. The association between ADPKD and abdominal aortic aneurysm (AAA) is rarely reported. Early detection is crucial due to the fatal risk of rupture.

Methods

Observational.

Results

A 65-year-old male farmer presented to Wahidin Sudirohusodo Hospital in Makassar, Indonesia, complaining of lower left abdominal pain that had been experienced for 1 month and was getting worse. He has a history of hypertension. On examination, he had elevated blood pressure (150/79 mmHg) and a pulsatile periumbilical left mass (6x5cm) accompanied by tenderness. A urine test found red blood cells in microscopic examination. Non-contrast abdominal Multi-Slice Computerized Tomography (MSCT) revealed bilateral multiple renal cysts and a fusiform abdominal aortic aneurysm (±11,57cm) with the largest outer to outer diameter ±6,5cm. These findings were consistent with the abdominal aorta CT angiography showed an infrarenal abdominal aortic fusiform aneurysm accompanied by thrombus, with diameter ±6cm outer to outer. The patient underwent complex vascular malformation reconstruction surgery. His clinical condition improved and he was allowed to go home on the 12th day after surgery.

Conclusion

A 65-year-old male with ADPKD and abdominal aortic aneurysm who successfully underwent complex vascular malformation reconstruction is reported.

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