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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Peritoneal dialysis (PD) accounts for only about 10 % of the dialysis population worldwide mainly due to the PD discontinuation. Clearly specifying the risk factors associated with transfer to HD in PD patients is a significant issue in PD patients.The glycated albumin (GA) to glycated hemoglobin A1c (HbA1c) ratio, a marker of blood glucose fluctuation and protein synthesis, has been associated with cardiovascular disease and mortality in patients undergoing hemodialysis (HD).However, its clinical significance in peritoneal dialysis (PD) remains unclear.
This single-center retrospective cohort study included patients who initiated PD between December 2007 and March 2020. Patients transferred from hemodialysis (HD) were excluded. The GA/HbA1c ratio was calculated at PD initiation, and participants were followed until PD cessation, death, or study completion (October 2021). The primary outcome was the time to transfer to hemodialysis (HD), defined as a switch from peritoneal dialysis (PD) to HD that lasted ≥ one month.
A total of 84 patients (median age: 60 years; diabetes mellitus [DM] prevalence: 40%) were included and classified into a low GA/HbA1c ratio group (<2.77, n=28) and a high GA/HbA1c ratio group (≥2.77, n=56), based on the cutoff value determined by receiver operating characteristic curve analysis. The median follow-up duration was 46 months. As candidate independent variables, we included age, sex, serum albumin, hemoglobin, estimated glomerular filtration rateand urinary protein. Log-rank tests revealed significantly lower HD transfer-free survival rates in the low GA/HbA1c ratio group than in the high GA/HbA1c ratio group (P < 0.001). Cox regression analysis with adjustment for potential confounders identified a low GA/HbA1c ratio as a significant risk factor for HD transfer (hazard ratio [HR] 3.23; 95% confidence interval [CI] 1.40–7.44; P=0.006). Sensitivity analyses using the cumulative incidence function and subdistribution hazard model confirmed similar results (HR 3.48, 95% CI 1.48–8.17; P=0.004). A subgroup analysis of non-DM patients yielded similar results (HR 6.83; 95% CI 1.70–27.46; P=0.007).
We found that the low GA/HbA1c ratio was strongly associated with transfer to HD in PD patients. Although the interpretation of the GA/HbA1c ratio has not been fully clarified, our study suggests that the GA/HbA1c ratio may be potentially reflect enhanced protein synthesis due to protein losses in urine and peritoneal dialysate.
