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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
In Japan, approximately one in five people has chronic kidney disease (CKD). Initiation of hemodialysis (HD) drastically changes lifestyles of patients .It is important for patients with CKD to anticipate the timing of HD initiation for their preparation. Some reports showed that the rate of decline in kidney function slowed after creation of arteriovenous fistula (AVF). However, there is no previous study that examined early changes in kidney function following AVF creation and kidney prognosis.We therefore investigated the association between early postoperative changes in kidney function after creation of AVF and the time to HD induction.
We conducted a retrospective, single-center cohort study. Patients who were hospitalized for AVF creation between April 2019 and August 2024 and who attended at least one postdischarge outpatient visit our division before HD induction were included. Exclusion criteria were: patients with AVF thrombosis before the first postoperative outpatient visit, patients who had undergone HD prior to creation of AVF, patients who had undergone peritoneal dialysis, patients who lost kidney function due to nephrectomy for kidney tumor and patients whose day of HD initiation was scheduled at the time of AVF creation.
The daily change in serum creatinine (ΔSCr/day) was calculated as the difference between serum creatinine (SCr) immediately before surgery and SCr at the first postdischarge outpatient visit, divided by the number of intervening days. The change in body weight between body weight immediately before AVF procedure and body weight at the first outpatient visit was defined as ΔBW. eGFR before the AVF procedure was collected from 1 year before the operation and GFR slope was calculated by ordinary least squares using outpatient measurements. We examined the association between ΔSCr/day and the time from the first outpatient visit to starting HD with Cox proportional hazards model. Missing values were complemented using multiple imputation by chained equations.
We analyzed 83 patients (68 men and 15 women) with a mean age of 70.3 ± 12.5 years. No one died after operation until initiation of HD, but one patient with severe dementia was lost to follow-up without induction of HD. Univariable analysis showed that ΔSCr/day was associated with a shorter time to HD initiation (hazard ratio (HR) 3.04 per 0.1 mg/dL/day; 95% confidence interval (CI), 1.80–5.14; p<0.001). In a multivariable model adjusted for sex, age, hypertension, diabetes mellitus, smoking status, medication of renin–angiotensin system inhibitors and eGFR immediately before surgery, the association remained significant (HR 2.89 per 0.1 mg/dL/day; 95% CI, 1.77–4.73; p<0.001). In a model additionally incorporating ΔBW or the preoperative eGFR slope, the increase in ΔSCr/day remained independently associated with earlier HD initiation.
Early postoperative change in kidney function was independently associated with the time to HD initiation. Our finding suggest that ΔSCr/day may be beneficial for clinicians, patients and their families in predicting the day of HD initiation.
