PREVALENCE AND OUTCOMES OF CEREBROVASCULAR DISEASE IN END-STAGE RENAL DISEASE PATIENTS ON MAINTENANCE HEMODIALYSIS: A CROSS-SECTIONAL STUDY

 

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https://storage.unitedwebnetwork.com/files/1099/1ff9df5ccc6c7d784b04fb98cc79dac5.pdf
PREVALENCE AND OUTCOMES OF CEREBROVASCULAR DISEASE IN END-STAGE RENAL DISEASE PATIENTS ON MAINTENANCE HEMODIALYSIS: A CROSS-SECTIONAL STUDY

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NORIDJA
YUSOP
NORIDJA YUSOP noridjayusop@cim.edu.ph CHONG HUA HOSPITAL NEPHROLOGY CEBU CITY Philippines *
CATHERINE TI chattertee@gmail.com CHONG HUA HOSPITAL NEPHROLOGY CCEBU CITY Philippines -
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Cerebrovascular disease remains one of the leading causes of morbidity and mortality in End-stage renal disease patients undergoing hemodialysis. Hemodialysis patients often present with multiple comorbidities including hypertension, diabetes, coronary/peripheral artery disease, malignancy, atrial fibrillation, dyslipidemia, bleeding dyscrasias, and even a history of COVID-19 infection – each of which is independently associated with an elevated risk of cerebrovascular event. Understanding the magnitude of this problem and the underlying mechanisms is crucial for developing targeted preventive strategies and improving patient outcomes. 

This is a retrospective, analytical, cross-sectional chart review study aimed at determining the prevalence and outcomes of patients on maintenance hemodialysis who succumb to cerebrovascular diseases. The chart review is utilized to gather the necessary data. 

More than half of the patients had ischemic stroke (60.78%) compared with those with hemorrhagic stroke (39.22%). Most affected were older patients in the 61-80 age group with only 1.96% under 40 years old. Thirty-three percent (33.33%) of these patients expired after acute cerebrovascular events and hemorrhagic stroke was associated with a markedly higher mortality rate (55.00% vs. 19.35%, p = 0.005), while ischemic stroke patients were more likely to be discharged improved (77.42% vs. 35.00%). 

End-stage renal disease patients undergoing hemodialysis are at significantly higher risk of cerebrovascular events compared to the general population. Ischemic stroke is more common compared to hemorrhagic stroke, with the latter requiring longer hospital stay and portends a poorer prognosis. Preventive measures such as control of comorbidities are essential in reducing the incidence of cerebrovascular events and improving overall outcomes in hemodialysis patients. 

Kewords