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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Anemia is a common complication of chronic kidney disease (CKD) and is associated with faster renal function decline and adverse clinical outcomes. However, its prognostic value in IgA nephropathy (IgAN) and potential sex-specific differences remain unclear. This study aimed to evaluate the association between hemoglobin (Hb) levels and the risk of progression to end-stage kidney disease (ESKD) in patients with IgAN.
This multicenter retrospective cohort study included 788 patients with biopsy-proven IgAN who were diagnosed and treated at two tertiary hospitals between 2002 and 2021. Patients were categorized into five groups based on Hb levels at the time of kidney biopsy (<11, 11–<12, 12–<13 [reference], 13–<14, and ≥14 g/dL). The primary outcome was progression to ESKD. Multivariate Cox proportional hazards models were used to evaluate independent associations, and subgroup analyses were performed according to sex.
During a median follow-up of 70 months, 66 patients (8.4%) progressed to ESKD. Lower Hb levels were significantly associated with increased risk of ESKD after multivariate adjustment (Hb < 11 g/dL; adjusted hazard ratio [aHR], 2.76; 95% confidence interval [CI], 1.19–6.42; P = 0.018). In sex-specific analyses, this association was significant in women (Hb < 11 g/dL; aHR, 5.02; 95% CI, 1.33–18.94; P = 0.017; 11 ≤ Hb < 12 g/dL; aHR, 4.64; 95% CI, 1.26–17.10; P = 0.021), whereas no significant association was observed in men. According to the Oxford classification, higher tubular atrophy/interstitial fibrosis (T) and endocapillary hypercellularity (E) scores were significantly associated with lower hemoglobin levels (P < 0.05).
Low Hb levels at the time of diagnosis were independently associated with an increased risk of progression to ESKD in patients with IgAN. The prognostic effect of anemia was particularly pronounced among women, suggesting a sex-specific vulnerability.
