CLINICOPATHOLOGICAL FEATURES AND PREDICTORS OF LUPUS NEPHRITIS PATIENTS: A STUDY IN A TERTIARY CARE HOSPITAL IN BANGLADESH.

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CLINICOPATHOLOGICAL FEATURES AND PREDICTORS OF LUPUS NEPHRITIS PATIENTS: A STUDY IN A TERTIARY CARE HOSPITAL IN BANGLADESH.

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Co-author 1

Dr. Farhana Faruque drsusan33@gmail.com Sir Salimullah Medical college Mitford Hospital Internal Medicine Dhaka Bangladesh *

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Introduction

Lupus Nephritis (LN) represents a severe manifestation of systemic lupus erythematosus, and its clinicopathological findings significantly impact the overall disease prognosis. Unfortunately, there is a scarcity of data on lupus nephritis (LN) in Bangladeshi patients in the existing literature.

Methods

This cross-sectional study was conducted at the Department of Sir Salimullah Medical College Mitford Hospital, Dhaka, Bangladesh from January 2023 to July 2023. The study included a total of 30 lupus nephritis patients, selected through purposive sampling. All data were analyzed by using the SPSS version 23.0program.

Results

In this study, the majority of participants (53.2%) belonged to the 24 years age group, with 77% being female. Regarding the classification of lupus nephritis according to the International Society of Nephrology/Renal Pathology Society (USN/RPS), the majority (53%) fell into class IV. Remarkably, all of our participants (100%) exhibited a SLEDAI 2K score of >20.

Conclusion

Among the Bangladeshi population, lupus nephritis is more prevalent in younger individuals and females. In the majority of lupus nephritis cases, ISN/RPS score IV is observed, and there is a higher frequency of having a SLEDAI 2K score of>20. In addition to the ISNRPS score, SLEDAI 2K scores can be regarded as another reliable diagnostic tool for evaluating lupus nephritis.

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