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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Diabetes mellitus, uma condição crônica e progressiva que afeta milhões de pessoas, é uma das principais causas de doença renal crônica (DRC). Com um aumento projetado para 1,3 bilhão de casos até 2050, estratégias não farmacológicas, como a prática regular de exercícios físicos, têm se destacado para a prevenção e o controle da doença, conforme recomendado pela Organização Mundial da Saúde (OMS). Objetivo: Avaliar o efeito do treinamento físico aeróbico moderado (TFA) sobre a função renal, hemodinâmica e perfil oxidativo em modelos de ratos com diabetes mellitus tipo 1 (DM2) e tipo 2 (DM2).
Wistar rats were randomized into the following groups: Citrate, t1DM, t2DM, t1DM+APT, and t2DM+APT. The APT consisted of a 28-day swimming protocol. Renal function (inulin clearance, serum creatinine and albuminuria), renal hemodynamics (renal blood flow-RBF, mean arterial pressure-MAP and renal vascular resistance–RVR), and oxidative stress (urinary peroxides, lipid peroxidation and renal thiols).
Aerobic physical training (APT) promoted a robust improvement in renal function, even with modest effects on hyperglycemia. The training increased inulin clearance by 40% in the t1DM+APT group and by 67% in the t2DM+APT group, while albuminuria was also reduced in t1DM group (31%) and in t2DM (16%). It was also observed that APT significantly reduced albuminuria in both DM groups. Renal hemodynamics evaluation showed an elevation in RBF, more pronounced in the t1DM+APT group, which was similar to the Citrate group. Furthermore, it was notably observed that APT reversed oxidative damage, as demonstrated by the reduction in the urinary peroxides and the elevation in the antioxidant levels in both DM groups subjected to the intervention.
Aerobic physical training demonstrated efficacy in renal protection in t1DM and t2DM models, observed through significant improvements in the Glomerular Filtration Rate (GFR), hemodynamics and oxidative profile. These findings reinforce the practice of physical exercise as a potent non-pharmacological strategy to delay the progression of diabetic kidney disease (DKD).
