IMPACT OF KIDNEY PALLIATIVE CARE ON SYMPTOM BURDEN IN ADVANCED CKD AND ESKD: A COHORT STUDY FROM MALAYSIA

 

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IMPACT OF KIDNEY PALLIATIVE CARE ON SYMPTOM BURDEN IN ADVANCED CKD AND ESKD: A COHORT STUDY FROM MALAYSIA

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Agni Nhirmal Kumar
Sugurmar
Agni Nhirmal Kumar Sugurmar agninhirmal@yahoo.com Hospital Tuanku Jaafar Seremban Nephrology Seremban Malaysia *
Asiah Usamah asiahusamah@gmail.com Hospital Tuanku Jaafar Seremban Nephrology Seremban Malaysia -
Anila Perumal sagi21ster@gmail.com Hospital Tuanku Jaafar Seremban Palliative Seremban Malaysia -
Iris Chung arisa_ko@hotmail.com Hospital Tuanku Jaafar Seremban Palliative Seremban Malaysia -
Brian Joe Anthony brianjoe1983@hotmail.com Hospital Tuanku Ampuan Najihah Nephrology Kuala Pilah Malaysia -
Muhd Zulfadli Hafiz Ismail m.zulfadli@moh.gov.my National Institutes of Health Sector of Biostatistics and Data Repository Shah Alam Malaysia -
Lily Mushahar lilymushahar@gmail.com Hospital Tuanku Jaafar Seremban Nephrology Seremban Malaysia -
 
 
 
 
 
 
 
 

Palliative care offers patient-centred health services aimed at improving the quality of life for both patients and their caregivers. Patients with advanced chronic kidney disease (CKD) and end-stage kidney disease (ESKD) often experience a high symptom burden, making symptom alleviation a central focus of care.

We conducted a retrospective cohort study of inpatients referred to the kidney palliative care team in 2023 in Negeri Sembilan, Malaysia. Of the 92 patients with baseline Edmonton Symptom Assessment System (ESAS) scores recorded upon admission, 44 had follow-up ESAS scores available for analysis. Data normality was tested using the Shapiro–Wilk test. Paired t-tests were used for normally distributed symptoms, and Wilcoxon signed-rank tests for non-normal data.

Kidney palliative care played a vital role in end-of-life support, with most patients managed conservatively and passing away at home—reflecting strong community and family involvement. Among the 44 patients who completed both baseline and follow-up ESAS assessments, significant improvements were observed in pain and nausea, while drowsiness worsened, likely due to treatment-related effects. These findings offer important insights into symptom progression and management within kidney palliative care.

Kewords