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E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
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Traditionally, nosocomial urinary tract infections (UTI’s) have higher preponderance for antimicrobial resistance (AMR). However, the recent spurt in AMR amongst community acquired UTI`s additionally is alarming. Lack of data regarding epidemiology and AMR pattern, emergence of newer pathogens with de novo AMR as well as a poor knowledge, attitude, belief and behaviour (KABB) towards antimicrobial usage in the general population has possibly led to the catastrophic health challenges in our country. In this study, the spectrum of microbes and antimicrobial resistance pattern of patients(pts.) with UTI in a critical care setup shall be compared with those having UTI’s in the community and outpatient setup.
A retrospective analysis of demographic data and urine cultures with antimicrobial sensitivity pattern of pts. presenting with UTI either in the ICU (Group A) or in outpatient (Group B) setting between January 2023 to December 2024 was done. A 15-point questionnaire based KABB survey regarding awareness about antimicrobial usage and AMR was given to patients, caregivers and visitors.
The first positive culture from 594 pts. of Group A and 2174 pts. of Group B had bacterial isolates as follows: Group A: E.coli- 44%, Klebsiella-34%, Pseudomonas-15%, Proteus-3%, Enterococcus-1%, Miscellaneous-3% and Group B: E.coli- 58%, Klebsiella-25%, Pseudomonas-8%, Proteus-4%, Enterococcus-4%, Miscellaneous-1%.
Table 1: Comparison of AMR pattern for Gram Negative Bacteria
Antibiotic
E.coli
Klebsiella
Pseudomonas
Proteus
Grp A
Grp B
Grp
A
B
Meropenem
44
33*
66
60*
58
32
6
2
Imipenem
45
34*
65
62*
59
31
5
3
Piperacillin+Tazobactam
62
51*
75
67*
61
40
3rd Gen. Cephalosporins
85
84
76*
41
47
47*
Cefoperazone+Sulbactam
48
37*
70
56
39
10
Amikacin
23
41*
46
19
20
Levofloxacin
80
78*
79
71*
68
64*
82
84*
For Gram Positive bacteria (predominant- enterococcus), resistance for Vancomycin was 26% and 18*%; whereas for Teicoplanin, it was 26% and 16*% in Groups A and B respectively.{*P value statistically significant (Pearson chi-square test)}.
1152 subjects surveyed. Only 45% were aware of what an “antibiotic” is; as many as 56% took antibiotics without prescription, 38% used leftover medications, 62% stopped the antibiotic course midway and 74% were unaware about the terms – antimicrobial or antibiotic resistance.
Similarity of spectrum of microbes causing UTI between critically ill hospitalized patients and outpatients, as well as lack of difference in the AMR pattern between these two groups is alarming and could be just the tip of the iceberg. Lack of awareness about AMR and unregulated antibiotic consumption in the general population will add fuel to the fire to this burning health issue.