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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Immune dysfunction is a critical problem amongst patients with chronic kidney disease, especially with patients receiving haemodialysis. The interaction between blood cells and artificial components of the blood circuit results in the intermittent release of acute inflammatory mediators into the bloodstream. As a result, patients receiving haemodialysis experience severe immune dysfunction characterized by acute inflammation induced by the haemodialytic procedure and chronic inflammation associated with uremia. Neutrophils are pivotal in the immune response, particularly in combating acute inflammation. Importantly, neutrophils in patients on haemodialysis are known to undergo cellular senescence due to cellular damage, uremic toxins, and reactive oxygen species (ROS), leading to a diminished capacity for phagocytosis and bactericidal activity against pathogens.
Hydrogen has been shown to relieve the oxidative stress in cells by reducing the levels of ROS including free radicals. Electrolyzed Water Haemodialysis (EW-HD) is a new system that uses electrolyzed water to add molecular hydrogen to the dialysis solution. EW-HD has recently been demonstrated to provide various beneficial effects, such as reduction of mortality and cardiovascular events, recovery from post-dialysis fatigue, and relief from itching. However, the specific impact of EW-HD on the immune system remains to be fully determined.
In this study, we conducted a comprehensive analysis of blood tests, including a complete blood count and a white blood cell differential, at a single institution and compared their data between regular HD and EW-HD. Statistical analysis was performed using the Student’s t-test, with a p-value of 0.05 or less considered statistically significant.
We found a significant reduction in neutrophil counts three months after transitioning from regular HD to EW-HD. Furthermore, the neutrophil-to-lymphocyte ratio, which is a marker of immune function, was significantly decreased following the switch to EW-HD, suggesting an improvement in immune function associated with this treatment modality. Clinically, a reduction in the frequency of infectious fever episodes was also observed after the transition to EW-HD.
These results suggest that hydrogen mediated by EW-HD may play a role in restoring neutrophil function. Consequently, EW-HD may contribute to the prevention of various infections by enhancing the functional capacity of neutrophils in patients undergoing haemodialysis.
