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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Higher ultrafiltration volumes in hemodiafiltration (HDF), a surrogate for convective dose, have been associated with improved survival. Whether this advantage is affected by patients' anthropometric characteristics (body mass index (BMI) or body surface area (BSA)) is unclear.
We analyzed individual patient data from 5 randomized trials to evaluate the association between convective volume and risk of all-cause mortality stratified by BMI and BSA. Cox proportional hazards models with interaction terms, Kaplan-Meier survival curves and multivariable spline models were used to explore potential nonlinear and joint effects.
Our cohort consisted of 2083 patients treated with HDF. Convective volume, BMI, and BSA were each categorized into tertiles (for volumes: 17.9 L (low), 22.8 L (medium), and 27.7 L (high); for BMI 20.9 kg/m (low), 25.2 kg/m (medium), and 31.7 kg/m (high); for BSA 1.57 m (low), 1.79 m (medium), and 2.03 m (high)). Higher convective volume was significantly associated with reduced all-cause mortality (HR 0.62, 95% CI: 0.49–0.78 for highest vs lowest tertile). In joint analyses, patients with medium or high BMI or BSA receiving high convective volume had the lowest mortality risks (HR: 0.53, 95% CI: 0.36–0.78). In contrast, the interaction between BSA and convection volume was less consistent and did not show a clear gradient (see Figures).
In patients receiving HDF, high ultrafiltration volumes were associated with significantly lower risk of all-cause mortality, particularly among those with medium to high BMI. This relationship was not consistently observed with BSA. It is plausible that BMI and BSA capture different physiological characteristics. BMI may reflect nutritional status or body composition, while BSA may be a proxy for uremic solute distribution volume. Ultrafiltration volume requirements may align more closely with BMI than BSA, indicating that BMI could be a more practical metric for personalizing convective volume in HDF to optimize patient outcomes.
