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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Acute kidney injury (AKI) is a major global health problem with high morbidity, mortality, and risk of progression to chronic kidney disease. Although its significance has been increasingly recognized, its full global health impact has not been quantified.
We conducted a global burden estimation of acute kidney injury (AKI) integrating data from a systematic review and meta-analysis of epidemiological studies (2013–2023) with international demographic and health system datasets. The systematic review followed PRISMA 2020 guidelines and included observational studies reporting AKI incidence or mortality, identified through PubMed and Scopus (searched on July 1, 2025). Eligible studies reported population-based or hospital-based data using KDIGO or RIFLE definitions. Pooled estimates were obtained using multilevel random-effects meta-analysis, adjusting for AKI detection methods, study period, and country or WHO region. Hospital-based incidence rates were standardized to person-years using catchment populations estimated from hospital bed density. Population size and life expectancy were retrieved from the World Bank; mortality distributions from the WHO mortality database; and hospital capacity data from the WHO Global Health Observatory. Years of life lost (YLL), years lived with disability (YLD), and disability-adjusted life years (DALYs) were calculated using standard burden of disease methods, assuming disability weight 0.5 and disease duration 1.5 months.
We screened 16,485 abstracts and included a total of 88 studies, which covered AKI epidemiological data from 35 countries and 6 WHO-defined regions. We estimated 40.8 million (95% CI: 31.02–53.73 million) incident AKI cases annually and 6.7 million (95% CI: 5.02–8.97 million) related deaths worldwide. The global burden was 40.4 million DALYs (95% CI: 30.2–53.9 million), predominantly contributed by YLL. The global DALY rate was 524 per 100,000 population, highest in the Americas 942 (95% CI: 553 – 1,606) per 100,000 population and lowest in South-East Asia at 126 (95% CI: 32 – 505) per 100,000 population. At the national level, Argentina, Japan, Malaysia, and Brazil exhibited the highest DALY rates, while India, Peru, and Pakistan were among the lowest. Uncertainty intervals were wide in regions with sparse data or small populations.
Acute kidney injury represents a substantial global health burden, with DALYs comparable to other major diseases. These findings highlight the urgent need for enhanced early detection, timely management, and structured post-AKI follow-up to mitigate its global impact.
