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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
TAFRO syndrome is a rare systemic inflammatory disorder characterized by thrombocytopenia, edema, fever, renal dysfunction, and organomegaly. Timely immunosuppressive therapy is essential; however, diagnosis is not easy for uncommon clinical presentation case.
A 51-year-old woman with no prior renal impairment presented with appetite loss and leg edema. She showed fever (38)proteinuria (3+), kidney impairment (sCr1.2 g/dl, eGFR 36.9 ml/min) and high CRP levels (9 mg/dL). CT image found unilateral kidney enlargement. Urine white blood cells were detected. Clinical diagnosis was Pyelonephritis, and antibiotics were given, but her symptoms were not ameriolated. Serum albumin were decreased to 2.2mg/dl, and systemic edema with bilateral pleural effusion were emerged, suspecting TAFRO syndrome.
Methylprednisolone pulse therapy (1 g/day for 3 days) was given, but there was no response. Tocilizumab (8 mg/kg) was initiated right after predonisolene. The patient became anuric and required hemodialysis. Following combined immunosuppressive therapy, inflammatory markers, renal function, and platelet count gradually improved. Serum IL-6 and VEGF were both elevated (124 pg/mL, 3743 pg/mL, respectively). Renal biopsy were not performed given the unilateral enlargement and her systemic condition. Bone marrow biopsy and flowcytometry showed fibrotic changes with increased megakaryocyte, confirming TAFRO syndrome.
We report a case of TAFRO syndrome initially misdiagnosed as pyelonephritis. Prompt induction of Combined prednisolone and tocilizumab therapy led to a favorable outcome, underscoring the importance of early recognition and aggressive immunosuppressive intervention in this potentially life-threatening condition.
