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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Non-tuberculous mycobacteria (NTM) are rare but increasingly recognized causes of peritoneal dialysis (PD)-related infections, often requiring prolonged treatment and posing risks of catheter removal or transfer to hemodialysis (HD). We have implemented unique approaches to managing NTM infections, including simultaneous standard bacterial and acid-fast bacilli testing in patients with suspected PD-related infection, and a modified catheter diversion procedure (CDP) that incorporates subcutaneous tissue debridement. This study aimed to evaluate the effectiveness of our strategy for PD-related infection caused by NTM.
A single-center, retrospective observational study was conducted at the Japanese Red Cross Medical Center, to review cases of PD-related infection caused by NTM between January 2013 and December 2022. Cases were identified based on positive acid-fast bacilli cultures, with duplicate and incomplete records excluded. Clinical characteristics, microbiological findings, surgical interventions, and patient outcomes were analyzed. In addition, patients with catheter-related infection (CRI) were divided into the early and late diagnosis groups based on whether NTM infection was recognized within 14 days of initial presentation, and clinical parameters were compared between the two groups.
Among the 22 eligible cases, the mean age was 63.9 ± 11.5 years. 17 cases (77%) were male patients. The mean PD vintage was 4.4 ± 2.9 years. In all cases, acid-fast bacilli testing was performed early in the clinical course. CRIs were eventually diagnosed in 20 cases, while peritonitis was observed in 2 cases. Notably, 18 cases (82%) did not cover the catheter exit site during daily showers. Major causative organisms were M. chelonae (11/22; 50%) and M. abscessus (6/22; 27%). Antibiotic therapies, primarily moxifloxacin, clarithromycin, and amikacin, were administered in all cases. Initial surgical interventions included CDP in 14 cases and catheter removal procedures in 6 cases. Among 14 cases that underwent CDP, 5 cases involved modified CDP with subcutaneous tissue debridement. Among 8 cases that eventually required catheter removal, 4 cases transferred to HD. Catheter removal was required in 2 cases following standard CDP as the initial surgical intervention, whereas no catheter removal was needed following modified CDP with subcutaneous tissue debridement. The proportion of positive acid-fast bacilli smear tests was 50% in the early diagnosis group and 27% in the late diagnosis group. Additionally, the proportion of cases with a positive result on the first acid-fast bacilli test was 80% in the early diagnosis group and 45% in the late diagnosis group. There was no significant difference in the duration of antibiotic therapy between patients diagnosed with CRI in the early and late diagnosis group.
Our PD program, which includes routine mycobacterial testing for suspected PD-related infections, may positively impact catheter preservation and PD continuation in cases of NTM-related infections. Therefore, routine and repeated acid-fast bacilli testing is essential for the appropriate diagnosis of PD-related infections caused by NTM. Further research is warranted to establish standardized strategies for the diagnosis and management of NTM-related PD infections.
