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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Multicystic dysplastic kidney disease (MCDK) is a congenital condition often misdiagnosed as hydronephrosis on antenatal ultrasound. Confirmatory renal scintigraphy is usually unavailable in resource-constrained settings, and data on the effectiveness of ultrasound in paediatric MCDK have been previously unreported in sub-Saharan Africa. The study aimed to determine the diagnostic accuracy of kidney ultrasound (KUB scan) for identifying paediatric MCDK, using a Mercaptoacetyltriglycine-3 scan ([99mTc]Tc-MAG3), differential renal function (DRF) as the reference standard.
This retrospective diagnostic accuracy study involved consecutive children under 13 years of age with suspected unilateral MCDK who underwent both kidney ultrasound and [99mTc]Tc-MAG3 scans within 6 to 8 weeks of presenting to the hospital between January 1, 2014, and December 31, 2023. Diagnosis required a KUB scan report stating characteristic radiological MCDK features and a [99mTc]Tc-MAG3 scan showing a DRF of zero. Data were extracted from hospital records. Diagnostic accuracy parameters were calculated, and the McNemar test was used to compare the response proportions of the KUB scan and the reference standard. Reporting adhered to the Standards for Reporting of Diagnostic Accuracy Studies (STARD) guideline. Ethical Approval HREC REF: 805/2024.
Among the 793 eligible children, the [99mTc]Tc-MAG3 classified 101/101 (100.0%) kidneys as non-functional. The KUB scan accurately identified 97/98 (99.0%) cases. Compared with [99mTc]Tc-MAG3, KUB scan sensitivity was 99.0% [95% Confidence Interval (CI): 95.6% – 99.9%], specificity: 99.9% [CI: 99.4% – 100.0%], positive predictive value: 99.0% [CI: 95.6% – 99.9%] and negative predictive value: 99.9% [CI: 99.4% – 100.0%]. Overall accuracy was 99.7%. Cohen’s kappa for agreement was 0.988 (substantial agreement), and the Area Under the Receiver Operating Characteristic curve was 0.995 [CI: 0.983 – 1.000]. Three missing KUB scan reports were excluded; sensitivity analysis considering them as false negatives (worst-case scenario) did not materially change results.
The postnatal kidney ultrasound scan performs excellently in diagnosing paediatric MCDK in the South African context. Consequently, confirming a solitary functioning contralateral kidney devoid of abnormalities with a renal scintigraphy scan is mostly unnecessary. This finding has clinical practice implications for paediatric nephro-urology locally and plausibly in other resource-constrained and resource-sufficient settings. Further research on healthcare resources and economic impacts will support contextual adaptation.
