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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Candidemia is a significant disease with a high mortality rate. While Candida primarily proliferates in the kidneys, making them the most frequently involved organ, diagnosis is challenging, resulting in rare reports of fungal granulomatous interstitial nephritis. We report a case of fungal granulomatous interstitial nephritis caused by Candida that developed during immunosuppressive therapy for COVID-19.
[Case] 61-year-old male.
[Medical History]
He was under outpatient care at a local hospital for diabetes and dyslipidemia. He contracted COVID-19 6 days prior to admission (X-6 days). On day X, his SpO2 decreased, and he was admitted to our hospital. He developed severe COVID-19, requiring mechanical ventilation and extracorporeal membrane oxygenation, from which he was weaned. However, on day X+32, his pneumonia worsened again, necessitating reinitiation of mechanical ventilation and steroid therapy. On day X+57, he developed candidemia. Although blood cultures became negative with antifungal therapy, β-D-glucan levels remained persistently elevated. On day X+103, he developed AKI, progressing to end-stage renal failure on day X+105, necessitating hemodialysis initiation. He died on day X+162 due to gastrointestinal hemorrhage. Autopsy revealed granulomatous interstitial nephritis caused by Candida.
This case presented multiple risk factors for invasive candidiasis: ICU admission, central venous catheter use, immunosuppressive therapy, and COVID-19 (recent studies suggest COVID-19 may impair the immune response against Candida). Although standard treatment for invasive candidiasis—antifungal therapy for 2 weeks after blood cultures became negative—was administered, the nephritis persisted. Diagnosing fungal granulomatous interstitial nephritis requires a renal biopsy, which is often difficult in patients with poor systemic condition. Development of simpler diagnostic methods is anticipated, and extending treatment duration to account for potential nephritis complications should be considered in susceptible hosts.
