Clinical Outcomes and Economic Burden of Catheter-Related Bloodstream Infection Among Patients Undergoing Outpatient Hemodialysis: A Single-Center Tertiary Hospital Study

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Clinical Outcomes and Economic Burden of Catheter-Related Bloodstream Infection Among Patients Undergoing Outpatient Hemodialysis: A Single-Center Tertiary Hospital Study

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Co-author 1

Irmingarda Gueco ipgstud@gmail.com The Medical City Section of Nephrology Pasig Philippines *

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Introduction

CRBSI is one of the major complications in patients on hemodialysis with central venous access, and ranks as the second leading cause of mortality among patients on hemodialysis following cardiovascular disease. This study investigated the association of hospitalization costs, outcomes, and clinicodemographic profile of CRBSI patients undergoing maintenance hemodialysis

Methods

A retrospective design using a chart review of all outpatient hemodialysis patients with documented CRBSI from 2018 to 2023. Patient clinical and demographic profiles, outcomes, and total hospitalization costs were reviewed.

Results

The overall cumulative CRBSI rate was 0.9 per 1000 catheter days. The presence of diabetes mellitus was associated with poorer outcomes, particularly prolonged hospital stay, increased CRBSI recurrence, and mortality rates. The average cost per hospitalization for CRBSI patients was PHP 338,069.70 (± 301,718.40), with medications accounting for the largest portion (PHP 54,825.85 ± 58,589.45) of the total cost.

Conclusion

This study found a low incidence rate of CRBSI, which falls within the target rate set by KDOQI. Despite its low incidence, CRBSI is associated with a significant economic burden, highlighting the importance of preventive measures to improve patient outcomes and reduce healthcare costs.

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