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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Acute kidney injury (AKI) is a serious complication of pediatric malaria, contributing significantly to morbidity and mortality, particularly in resource-limited settings such as Sudan. This study compared demographic characteristics, kidney function, and outcomes between Sudanese children with malaria with and without AKI.
We conducted a retrospective cohort study of pediatric patients diagnosed with malaria and treated at Soba University Hospital (SUH), a tertiary referral center in Khartoum, Sudan, between 2014 and 2023. Malaria severity was classified according to World Health Organization (WHO) criteria. Patients were grouped into three categories: (1) severe malaria with AKI (n=70), (2) severe malaria without AKI (n=106), and (3) uncomplicated malaria (n = 120). We recorded descriptive statistics for age, sex, and laboratory parameters at hospital admission, including blood urea nitrogen (BUN), creatinine, hemoglobin, potassium, sodium, leukocyte count, malaria species, and clinical outcomes. Group comparisons were performed using one-way analysis of variance (ANOVA), with P-values adjusted for multiple testing. Kaplan-Meier and Cox models were used to evaluate survival as the outcome, with demographic and laboratory variables as predictors.
We included 296 pediatric patients in this analysis. The mean ± SD age was 5.7 ± 4.9 years, and 163 (55.1%) were male. Patients with severe malaria and AKI (n = 70) were significantly older than those with severe malaria without AKI (n = 106) and those with uncomplicated malaria (n = 120; Table 1). Serum creatinine and urea levels at admission were markedly elevated in the AKI group compared to the other groups (p < 0.0001). Crude mortality rates were 17.9% in severe malaria without AKI and 14.3% in severe malaria with AKI. Median survival time was significantly shorter in patients without AKI (9 days; 95% CI 7-9) compared to patients with severe malaria with AKI (17 days; 95% CI 15-17; p=0.0087; log-rank test). Among the lab data at admission, high leukocyte counts, low hemoglobin, and low potassium were significantly associated with higher mortality. No association with mortality was observed for age, sex, creatinine, and urea at admission.
Contrary to reports in the literature, we report that in hospitalized patients with severe malaria, mortality was lower in patients with AKI when compared to those without AKI. Close monitoring and intensive care in AKI patients may have been related to these favorable outcomes.
