SURVIVAL PROFILE AND ASSOCIATED FACTORS AMONG HEMODIALYSIS PATIENTS AT MUKOMUKO HOSPITAL

 

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https://storage.unitedwebnetwork.com/files/1099/901883022620e3b6fc0260a92af12b9a.pdf
SURVIVAL PROFILE AND ASSOCIATED FACTORS AMONG HEMODIALYSIS PATIENTS AT MUKOMUKO HOSPITAL

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Ester
Morina
Ester Morina estermorinasilalahi@gmail.com Hemodialysis Unit, Mukomuko Hospital, Bengkulu, Indonesia Internal Medicine Department Mukomuko Indonesia *
Calvin Sanjaya calvinsanjaya811@gmail.com Hemodialysis Unit, Mukomuko Hospital, Bengkulu, Indonesia Internal Medicine Department Mukomuko Indonesia -
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Chronic kidney disease (CKD) is a global health problem with a steadily increasing prevalence. The 2021 Global Burden of Disease (GBD) study reported 673 million cases worldwide, while in Indonesia the prevalence is 0.38%. Hemodialysis remains the main therapy for end-stage CKD. However, patient mortality is still high. This challenge is even greater in remote areas such as Mukomuko Regency, where limited access to hemodialysis units, low patient awareness of its importance, and socioeconomic barriers further complicate efforts to improve survival. To date, no data have described the profile of hemodialysis patients in Bengkulu Province. This study aims to be the first to assess the survival of chronic kidney disease patients undergoing hemodialysis at Mukomuko Hospital and in Bengkulu Province.

This was a retrospective cohort study. Data were collected from the medical records of hemodialysis patients at Mukomuko Hospital between June 2020 and July 2025. A total sampling technique was used. Data were analyzed with STATA 12. Univariate analysis described patient characteristics, bivariate analysis used the Chi-square test, and variables with p<0.25 were included in a multivariate logistic regression model.

This study included 175 patients treated with hemodialysis. The median age was 52 years, and 73.7% of patients were over 60 years old. The majority of patients were females (54.9%), and hypertension was the most common comorbidity (63.9%). Most patients (69.1%) used a central double-lumen (CDL) vascular catheter. The median duration of hemodialysis was 20 months, and 44% of patients had undergone hemodialysis for more than 24 months. Almost all patients had anemia, with a mean hemoglobin level of 8.45 g/dL. The median urea was 172 mg/dL, the median creatinine was 9.85 mg/dL, and the glomerular filtration rate (GFR) was 5 mL/min/1.73 m². Bivariate analysis showed that hemodialysis duration of less than 12 months was significantly associated with patient mortality (p<0.001). Other variables such as age, gender, comorbidities, vascular access, dialyzer type, hemoglobin, anemia, urea, creatinine, and GFR were not significantly associated. Multivariate analysis confirmed that only hemodialysis duration of less than 12 months remained significantly associated with patient survival (p=0.006).

Our results suggest that 38.9% of patients undergoing hemodialysis at Mukomuko Hospital died between June 2020 and July 2025. A hemodialysis duration of less than 12 months is a significant factor influencing patient survival at Mukomuko Hospital between June 2020 and July 2025. Further research is needed with more comprehensive data including hemodialysis adequacy, nutritional status, infections, dialysis-related complications, and psychosocial factors is needed to better understand patient survival.

Kewords