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Preparing your E-Poster
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E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
There are limited studies about vascular access (VA) of polycystic kidney disease (PKD) patients (pts) treated by haemodialysis (HD). Aim: To analyze the VA profile of incident HD pts with PKD in Catalonia, Spain.
Data from the Catalan Renal Registry of 23,243 adult pts (1486 with PKD and 21,757 non-PKD) starting HD therapy were examined over a 26-year period (1997-2022). Propensity score matching (PSM) methodology was performed to obtain a control group from non-PKD patients (1167 matched pairs were obtained).
The first VA used for starting HD in pts with and without PKD was: fistulae AVF (70.3%, n=820 vs 57.4%, n=670; p<0.001), graft (1.9%, n=22 vs 1.5%, n=18; p=0.52), tunnelled catheter (13.3%, n=155 vs 21.8%, n=254; p<0.001) and non-tunnelled catheter (14.6%, n=170 vs 19.3%, n=225; p=0.002).
Probability of starting HD by AVF, after adjusting for gender, age, end-stage kidney disease presentation, cardiovascular disease, body mass index and functional status (multivariate logistic regression analysis), was independently associated with PKD (odds ratio 1.66 [95% CI: 1.38–1.99], p<0.001).
Through a competing risk model, the hazard ratio (HR) for receiving a kidney graft (KG) within five years from starting HD, depending on the first VA used (AVF vs catheter), was: 1.74 (95% CI: 1.43-2.12, p<0.001) for PKD pts and 1.62 (95% CI: 1.35-1.93, p<0.001) for non-PKD pts. In comparison with non-PKD pts that started HD by AVF, HR of PKD pts for receiving a KG within five years from starting HD by AVF was 0.99 (95% CI: 0.87-1.14, p=0.97). In comparison with non-PKD pts that started HD by catheter, HR of PKD pts for receiving a KG within five years from starting HD by catheter was 0.96 (95% CI: 0.76-1.19, p=0.68).
The HR of death within five years from starting HD, depending on the first VA used (catheter vs AVF), was: 1.93 (95% CI: 1.45-2.57, p<0.001) for PKD pts and 1.43 (95% CI: 1.13-1.81, p=0.003) for non-PKD pts. In comparison with PKD pts that started HD by catheter, HR of death for non-PKD pts within five years from starting HD by catheter was 1.24 (95% CI: 0.95-1.64, p=0.12). In comparison with PKD pts that started HD by AVF, HR of death for non-PKD pts within five years from starting HD by AVF was the 1.64 (95% CI: 1.29-2.09, p<0.001).
1) Although AVF was the main type of VA used for starting HD in pts with and without PKD, the percentage of AVF was significantly lower in non-PKD pts at the expense of catheter. 2) PKD was an independent factor associated with a 66% greater probability of starting HD by AVF. 3) In pts both with and without PKD, starting HD through AVF or catheter was associated with the highest or the lowest probability of receiving a KG over time, respectively. 4) Among all pts starting HD through AVF, the presence of PKD confers an added advantage for reducing the risk of mortality over time. Abstract submitted at the 41st Annual Meeting of the Catalan Society of Nephrology.
