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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Females typically outlive males in the general population, but it is unclear whether this survival advantage persists among individuals who develop stage 5 chronic kidney disease (G5-CKD). We examined sex differences in mortality and receipt of kidney replacement therapy (KRT) among adults with incident non–KRT-dependent G5-CKD.
We conducted a population-based cohort study using linked administrative health and kidney care program data from Alberta, Canada. Adults 18 years or older with incident G5-CKD between April 2005 and March 2019 were followed until death, out-migration, or March 2021. Sex was defined as male or female as recorded in the provincial registry database. Sex-specific, age-stratified standardized mortality ratios (SMRs) were calculated using general population mortality rates data. Five-year probabilities of all-cause death, receipt of maintenance dialysis, and kidney transplantation were estimated with multi-state models, stratified by age and presence of diabetes or cardiovascular disease.
Among 7,506 individuals with incident G5-CKD, 54.9% were male (median age: 70 years for males, 74 years for females). Median follow-up was 7.9 years. Compared with the general population, females had greater excess mortality than males, particularly at younger ages (<55 years: SMR 40.9 [95% CI, 34.6–47.3] vs 15.9 [13.5–18.2]); this difference diminished with increasing age. Within the G5-CKD cohort, 5-year all-cause mortality risk was higher in younger females than in males (<55 years: 20.7% vs 14.6%) and similar between sexes at older ages. Regardless of major comorbidity, females under 65 years were less likely to receive a kidney transplant, and those ≥65 years were less likely to transition to receiving dialysis or transplantation.
In a universal healthcare setting, the female survival advantage observed in the general population was absent or even reversed after the development of G5-CKD. Females were less likely to receive kidney replacement therapy, independent of comorbidities. These findings suggest that differences in treatment decision-making or inequities in access to KRT, including transplantation, may contribute to poorer outcomes in females, especially at younger ages. Further investigations are warranted to understand the potential underlying structural, social, and biological mechanisms.
