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Preparing your E-Poster
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E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Peritoneal dialysis (PD) is a home-based dialysis modality that preserves residual kidney function and is associated with higher quality of life and greater patient autonomy compared to hemodialysis. Sustaining PD therefore has clear clinical benefits, particularly in aging societies. Although various studies have investigated risk factors for PD withdrawal, findings remain inconsistent and sometimes conflicting. In this study, we aimed to identify predictors of PD withdrawal in a Japanese single-center cohort.
We retrospectively analyzed 65 adult patients who initiated PD at our hospital between January 2018 and April 2025. Clinical and laboratory data were systematically collected from electronic medical records and analyzed. The primary outcome was PD withdrawal, defined as transition to hemodialysis for ≥6 consecutive months, kidney transplantation, or death from any cause. Cox proportional hazards models were used to evaluate risk factors associated with PD withdrawal.
The median age of patients was 64 years (interquartile ranges [IQR], 53-73 years). Based on the initial peritoneal equilibration test, 7 patients (13%) were classified as high transporters, 21 (39%) as high-average, 22 (41%) as low-average, and 4 (7%) as low. The underlying kidney diseases were diabetic nephropathy in 25 patients (37%), chronic glomerulonephritis in 11 (16%), nephrosclerosis in 10 (15%), and other causes in 7 (11%). During the median follow-up period of 36 months (IQR, 23-51 months), 45 patients (69.2%) discontinued PD. Among those who discontinued PD, the median time from PD initiation to withdrawal was 31 months (IQR, 19-51 months). One-, three-, and five-year technique-survival rates were 86.1% (95% confidence intervals [CI] 78.1–95.0), 55.8% (95% CI 44.8–69.6), and 25.4% (95% CI 15.3–42.2), respectively. The most common cause of PD withdrawal was fluid overload, observed in 18 patients (40%), followed by death in 12 (27%), uremia in 5 (11%), and peritonitis in 5 (11%). During the follow-up period, 16 patients were hospitalized at least once for congestive heart failure (CHF), including 13 (81%) with one admission, 2 (13%) with two admissions, and 1 (6%) with four admissions.[AT1] [MOU2] The median time from PD initiation to the first CHF hospitalization was 13.5 months (IQR, 7.0-24.3 months) [AT3] [MOU4] in these 16 patients. Among them, 14 (88%) eventually discontinued PD; in this subgroup, the median time from the first CHF hospitalization to PD withdrawal was 9.5 months (IQR, 4.0-19.0 months)[AT5] [MOU6] . In multivariable analysis, male sex (hazard ratios [HR] 3.85; 95% CI 1.36–10.9; P = 0.011) and CHF hospitalization during the follow-up period (HR 10.8; 95% CI 3.68–31.8; P <0.001) were identified as independent predictors for PD withdrawal.
Male sex and intercurrent CHF hospitalization during the follow-up period may predict PD withdrawal.