FACTORS ASSOCIATED WITH PALLIATIVE CARE CONSULTATION IN HEMODIALYSIS PATIENTS WITH POOR PROGNOSIS: A SINGLE-CENTER STUDY FROM BANGKOK, THAILAND

 

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https://storage.unitedwebnetwork.com/files/1099/f24fb120a86c99be5540833a79cfb539.pdf
FACTORS ASSOCIATED WITH PALLIATIVE CARE CONSULTATION IN HEMODIALYSIS PATIENTS WITH POOR PROGNOSIS: A SINGLE-CENTER STUDY FROM BANGKOK, THAILAND

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Natanong
Thamcharoen
Natanong Thamcharoen natthamcharoen@gmail.com King Chulalongkorn Memorial Hospital Cheewabhibaln Palliative Care Center Bangkok Thailand *
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Patients with End-Stage Kidney Disease (ESKD) face a poor prognosis, yet the rate of palliative care (PC) consultation in this population remains low despite international recommendations. This study aimed to identify factors associated with PC consultation in a single hemodialysis unit in Bangkok, Thailand.

This was a single-center, cross-sectional study. We screened ESKD patients receiving maintenance hemodialysis at Benchakitti Park Hospital for the presence of poor prognostic factors, defined as any of the following: (1) Age > 80 years, (2) other advanced organ failures (3) metastatic cancer, or (4) Palliative Performance Scale (PPS) ≤ 40. Patient age, PPS, and hemodialysis vintage were compared between patients who received PC consultation and those who received regular care using a two-sample t-test. Sex, Goal of care (GoC) discussion and death were compared using Fisher's exact test. A P value of < 0.05 was considered statistically significant.


Forty-five patients with poor prognostic factors were identified (mean age: 81 years; 44.4% male). Ten patients (22.2%) were referred for PC consultation. Compared to patients receiving regular care, those who received PC had a significantly lower mean PPS (39.0 vs. 54.4, P < 0.05) and a longer mean hemodialysis vintage (49.5 months vs. 28.3 months, P < 0.05). There were no statistically significant differences in mean age or sex between the groups. Importantly, Goals of Care discussions occurred in 90% (9/10) of the PC group but in none of the regular care patients (0/35). The 2-year mortality rate for the overall cohort was 22.2% (10/45) (Table 1).

Table 1 Result

Characteristic/OutcomeRoutine care (N 35)Palliative care (N 10)P value

Sex (Male)

Mean age (Years)

Mean Palliative Performance Score (PPS)

Dialysis vintage (mean, months)

Goal of care discussion (N)

Death (N)

14 (40%)

81.5

54.4

28.3

2 (5.7%)

6 (60%)       

81.8

39

49.5

9 (90%)

8 (80%)

0.26

0.90

< 0.05

< 0.05

< 0.05

< 0.05

Palliative care consultation is uncommon for hemodialysis patients with poor prognostic factors. Referral was significantly associated with a lower functional status (PPS) and longer time on dialysis (vintage). The finding that these patients had a significantly higher rate of GoC discussions highlights the benefit of PC. Our data suggests that PC is often consulted late in the disease trajectory when patients are functionally declined or near the end of life, implying a need for increased awareness among nephrologists for earlier, proactive integration of palliative care.

Kewords