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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Severe heat stroke with acute kidney injury (AKI) is the most critical form of heat-related illness, characterized by multiple organ dysfunction. This study aimed to investigate prognostic factors affecting clinical outcomes in patients with severe heat stroke complicated by AKI.
We conducted a retrospective cohort study of 21 patients with severe heat stroke and AKI admitted to the intensive care unit of Toyama Prefectural Central Hospital between October 1, 2016, and August 31, 2025. Patients were divided into two groups according to the occurrence of adverse events, defined as in-hospital death or initiation of maintenance dialysis. Baseline characteristics and clinical parameters were compared between groups. Statistical analyses were performed using R software.
Four patients (19%) experienced adverse events: three patients died within 48 hours of admission, and one required maintenance dialysis. The event group showed significantly higher mean deep body temperature on admission (the event group: 40.75 ± 1.58 vs. the non-event group: 39.22 ± 1.15°C, p<0.05), Sequential Organ Failure Assessment (SOFA) score (9.5 ± 1.73 vs. 4.41 ± 3.57, p<0.05), and Acute Physiology and Chronic Health Evaluation (APACHE) II score (29.25 ± 3.59 vs. 14.06 ± 7.14, p<0.001 ) compared with the non-event group. Mechanical ventilation (4 [100%] vs. 0 [0%], p<0.001) and continuous kidney replacement therapy (2 [50%] vs. 0 [0%], p<0.05) were more frequently required in the event group. Although serum creatinine (Cr) on admission was similar between groups (1.94 ± 0.5 vs. 2.05 ± 1.15 mg/dL, p=0.85), Cr at 24 hours increased in the event group but decreased in the non-event group (3.08 ± 0.19 vs. 1.36 ± 0.95 mg/dL, p<0.001). Lactate dehydrogenase (LDH) on admission was also higher in the event group (477.5 ± 132.16 vs. 283.18 ± 112.73 mg/dL, p<0.05). Creatine kinase (CK) at 24 hours was markedly higher in the event group compared with the non-event group (median, 13660 [7996–28,453] vs. 1241 [128–2529] U/L, p<0.05). Other organ complications and comorbidities were comparable between groups.
Elevated SOFA and APACHE II scores, higher deep body temperature, increased LDH on admission, and increased CK on 24 hours, along with deterioration of renal function within 24 hours, may be associated with adverse outcomes in patients with severe heat stroke complicated by AKI. Our results indicate that these factors may provide a basis for risk stratification in patients with severe heat stroke complicated by AKI.
