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During the congress, E-Posters will be accessible to all participants on the congress website 24/7, as well as in the E-poster stations in the congress center.
Preparing your E-Poster
Please review the E-Poster format requirements carefully when preparing your E-Poster. Should your E-Poster not meet the mentioned requirements, it may not be displayed as described above.
E-Poster Submission Deadline
Please prepare and upload your E-Poster no later than March 14, 2026 11.59PM CET. After this date, you will no longer be able to prepare and upload your E-poster and it will not be displayed and accessible on the congress website.
Please follow the instructions below to input your abstract title.
Abstract titles should be brief and reflect the content of the abstract.
Infectious agents can pose a significant challenge in renal transplantation as they have the potential to cause direct infections in the renal graft. These infections can lead to impaired renal function and reduced graft survival. The most common post-transplant allograft infections include bacterial pyelonephritis and BK virus infection, while other etiological agents are less frequent but can also lead to significant allograft dysfunction. Our study aims to evaluate the histopathological reports of renal allograft biopsies performed between January 2016 and December 2023, obtaining data related to the frequency of different types of infections in renal biopsies.
A total of 8288 renal allograft biopsies were analyzed. The main indications for biopsy were "acute renal dysfunction," followed by "subnephrotic proteinuria" and "unspecified hematuria." Of the total number of biopsies, infectious diseases were identified in 822 cases (9.92%).
Of the total number of biopsies, infectious diseases were identified in 822 cases (9.92%). Among these, 559 (6.75%) were acute pyelonephritis of probable bacterial origin, 251 (3.03%) were cases of polyomavirus infection, and 12 (0.14%) were cases of other less common infections in the renal graft, such as leishmaniasis, Trypanosoma cruzi, fungal infections, tuberculosis, cytomegalovirus, and adenovirus. The histopathological features of these infections are characterized by the pattern of inflammatory cells in the infected area, as well as the presence of cellular atypia, special stains, and/or immunohistochemical studies that can predict the etiological agent. Some cases were further complemented with studies by electron microscopy, bacterial and fungal cultures, or PCR testing. However, it is important to note that these biopsies need to be evaluated by experienced pathologists, as the differential diagnosis of interstitial inflammation in renal allografts almost always includes T cell-mediated rejection, which has a very different treatment approach from allograft infections.
Therefore, it is important for clinicians to be able to identify and appropriately manage renal transplant recipients, indicating renal biopsy when necessary for adequate diagnostic evaluation of the patient, as accurate identification of infectious agents is crucial for appropriate treatment and improved outcomes in renal transplant patients, avoiding empirical immunosuppressive treatments that may lead to potentially unfavorable outcomes.
