Female Gender as a Risk Factor for Kidney Transplant Failure in the Dominican Republic

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E-Poster

https://storage.unitedwebnetwork.com/files/184/46ab757dc242f28c6bba6b4399a99a49.pdf

Abstract Title

First Name *

Eliana

Last Name *

Dina-Batlle

Co-author 1

Priscilla Batlle priscillabatlle99@gmail.com Hospital Metropolitano de Santiago Centro Renal HOMS Santiago de los caballeros

Co-author 2

Grupo Colaborativo Registro Biopsia Renal RD Grupo Colaborativo Registro Biopsia Renal RD dradina@mac.com Grupo Colaborativo Registro Biopsia Renal RD Grupo Colaborativo Registro Biopsia Renal RD Santo Domingo

Co-author 3

Anthony Gutierrez aj.gutierrez@ce.pucmm.edu.do Pontificia Universidad Catolica Madre y Maestra Facultad Ciencias de la Salud Santiago

Co-author 4

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Introduction

Kidney transplantation is the treatment of choice for end-stage renal disease, but rejection remains a concern. Factors like patient sex may influence outcomes, but effects are controversial.

Methods

A retrospective-observational cohort study was performed in which 142 biopsies of transplant recipients participated. Biopsy data from transplanted patients in the Dominican Republic were analyzed through the National Registry of Renal Biopsies, particularly concerning gender differences in rejection rates. These findings were compared with international studies to obtain a deeper understanding.

Results

Unlike some international studies that show a higher survival rate in women, this study revealed that women in the Dominican Republic are more likely to develop chronic renal transplant rejection. Men had approximately 722.74 more days than women before presenting with a biopsy showing evidence of rejection. While international studies show a higher survival rate in women, this study revealed that women in the Dominican Republic are more likely to develop chronic renal transplant rejection.

Conclusions

In the Dominican Republic, female sex associates with higher risk and shorter graft survival, contrasting with most studies. Further research on socioeconomic factors is needed to explain this discrepancy.

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