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Kidney transplantation is treatment of choice for end-stage chronic kidney disease. However, in our center different outcomes has been observed at short-term period in renal function and mortality without having found the risk factor associated. Therefore this paper looking for evaluate the delayed graft function (DGF) as risk factor associated on graft survival and patient mortality.
A nested case-control study, retrospective, open-label, non-randomized, was developed. Inclusion criteria was patients > 18 years of age, with kidney transplants from living and cadaveric donors performed in a mexican national medical center between 2015 and 2019, whom required renal replacement therapy within 7 days post-transplant period. The primary outcome was to identify the risk factors associated with delayed graft function and mortality at one year, through logistic regression to calculate OR. The secondary outcome was the evaluate survival after one year through survival curves with Kaplan-Meier with Long Rank Test to evaluate the significance between those with and without DGF.
A delayed graft function was associated with an increase in the kidney lost function and mortality for all causes in one year kidney transplantation follow up.