ASSOCIATION BETWEEN COGNITIVE PERFORMANCE AND PHYSICAL ACTIVITY IN YOUNG ADULTS WITH CHRONIC KIDNEY DISEASE ON DIALYSIS

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E-Poster

https://storage.unitedwebnetwork.com/files/1099/011e5294504e0a0a92eaf86133826b23.pdf

Abstract Title

First Name *

Xociquetzalli

Last Name *

Tejeda Castellanos

Co-author 1

Benjamin Rodriguez Espino rodriguezespinoba@gmail.com Hospital Infantil de México Federico Gómez Unidad de Investigación en Nefrologia CDMx

Co-author 2

Juan Manuel Ardavin jmardavin@santacarmen.mx Médica Santacarmen Nefrologia CDMx

Co-author 3

Olynka Vega Vega olynkavega@hotmail.com Instituto Nacional de Ciencias Médicas y la nutricion Salvador Zubiran Nefrologia CDMx

Co-author 4

Rafael Valdéz Ortiz rafavaldez@gmail.com Hospital General de México Nefrologia CDMx

Co-author 5

Mara Medeiros medeiro.mara@gmail.com Hospital Infantil de México federico gómez Unidad de Investigacion en Nefrologia CDMx

Co-author 6

Co-author 7

Co-author 8

Co-author 9

Co-author 10

Co-author 11

Co-author 12

Co-author 13

Co-author 14

Co-author 15

Introduction

Cognitive deficit in patients with CKD is associated with worse clinical outcomes and
can affect up to 80% of this population. Physical activity has been shown to improve the markers for
this deficit in other populations, with little evidence in young adult patients with CKD, where the
association between these variables is limited. We aimed to analyze the association between cognitive
performance and physical activity in young adults with chronic kidney disease on dialysis
replacement therapy.

Methods

Analytical cross-sectional observational study in dialysis units of
third-level and second-level institutes. We applied three questionnaires; the MoCA test, IPAQ-SF, and
KDQOL (cognitive and physical subscales). We used the phi coefficient for association analysis.

Results

Data were obtained from 55 patients, with a median age of 27 years and an interquartile
range of 24 to 28 years. Fifteen patients had a history of having received a kidney transplant, and
58.2% had been on another type of dialysis. 56.4% of the participants reported insufficient physical
activity, and 81.8% of the sample presented some cognitive deficit. Patients with sufficient physical
activity showed less frequency of cognitive deficit (difference in proportions 0.342; p<0.001). The
domains of cognitive performance most frequently altered were language (89.1%), attention (81.8%),
and visuospatial skills (65.5%). The sample averaged 95 points on the KDQOL questionnaire, with
no differences between groups. We observed that physical activity is associated with cognitive
performance with a value of phi=0.44 p=0.001.

Conclusions

Cognitive performance is affected in
up to 80% of patients with CKD; strategies on education related to physical activity could reduce the
frequency of this complication.

This abstract has been presented in the ALANEPE Congress

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