HYPOKALEMIA AND ITS CLINICAL ASSOCIATION IN PERITONEAL DIALYSIS

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https://storage.unitedwebnetwork.com/files/1099/c76ec2337bb156bfe0e7218987101d94.pdf

Abstract Title

First Name *

Milagros Melissa

Last Name *

Flores Fonseca

Co-author 1

Viridiana Rodríguez Ugarte viridianarodriguezugarte@gmail.com Instituto Mexicano del Seguro Social Nefrologia Queretaro

Co-author 2

Miguel Salvador Aguilera Rubalcava miguel-s.aguilera@hotmail.com Instituto Mexicano del Seguro Social Nefrologia Queretaro

Co-author 3

Gabriel Davila Castillo gdc94@live.com.mx Instituto Mexicano del Seguro Social Nefrologia Queretaro

Co-author 4

Sandra Fabiola Velasco Ramirez sandra.vramirez@academicos.udg.mx Centro Universitario de Ciencias Exactas e Ingeniería. Universidad de Guadalajara Quimica Guadalajara

Co-author 5

Co-author 6

Co-author 7

Co-author 8

Co-author 9

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Introduction

Hypokalemia is common disorder in peritoneal dialysis patients. Some studies have shown associations of its levels with all-cause mortality. Here, we conducted a study to identify frequency and the association between peritonitis and hypokalemia.

Methods

A single center, retrospective study in a tertiary Hospital in Queretaro, Mexico. A consecutive sample was approached. Serum potassium (SK) levels and degree of hypokalemia were analysed with peritonitis. Differences were compared using 2 chi-squares for categorical variables. Relationship were assessed using Pearson correlation coefficients. All statistical tests were performed using SPSS 28.0 and a P < 0.05 level of significance.

Results

There were a total 125 patients, 49 patients (40%) with hypokalemia (53.7 in the cohort. Mean age of 52, 54% were men, 32% known for diabetes. Hypokalemia showed significant correlation with serum creatinine, cholesterol levels, albumin, phosphorus and PTH intact levels. Also, low serum potassium levels below 4 mEq/L showed statistically significance with peritonitis (p=0.008).

Conclusions

Hypokalemia shows and association with more peritonitis episodes. In addition, hypokalemia showed lower nutritional serum biochemical markers. There results provide preliminar information that could help us understand the metabolic alterations associated in peritonitis episodes in PD patients.

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