ACCEPTANCE AND WILLINGNESS OF LIVING KIDNEY DONATION AMONG RELATIVES OF PATIENTS UNDERGOING HEMODIALYSIS IN BURKINA FASO

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Abstract Title

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Patrice

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ZOEHINGA

Co-author 1

Yeremadé Juste BONZI y_binzi@yahoo.fr CHU Yalgado Ouedraogo Nephrology Ouagadougou

Co-author 2

Abou COULIBALY samsoncoul@gmail.com Health Sciences Research Institute Epidemiology Kaya

Co-author 3

Gérard COULIBALY coulibalygerard@hotmail.fr CHU Yalgado Ouedraogo Nephrology Ouagadougou

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Introduction

Kidney transplantation is the best treatment for CKD stage 5. The current context in Burkina Faso only allows for living kidney donation. The main of our study was to investigate the acceptance of the principle and willingness of living kidney donation among relatives of patients undergoing hemodialysis in Burkina Faso.

Methods

We conducted a cross-sectional survey from December 7, 2022, to January 20, 2023, among first- and second-degree relatives and spouses of patients undergoing hemodialysis in Burkina Faso. Data were analyzed with STATA software. We performed a simple logistic regression to search for factors associated with the dependent’s variables. The odds ratios (OR) with their 95% confidence intervals were calculated and assessed using the Wald test. The significance threshold was set at 0.20. Significance variables were used for multiple logistic regression by step-by-step ascending. We retained the final model with variables having a p-value < 0.05. Study was approved by Burkina Faso Ethics Committee for Health Research (deliberation n°2022-12-268).

Results

Five hundred and fourteen (514) relatives of hemodialysis patients participated in the study. The mean age was 38.83 ± 10.58 years with a sex ratio of 1.32. In the relatives of hemodialysis patients 91.83% accepted the principle of living kidney donation and 75.68% were favor of donating a kidney to their relative. Source of information about kidney transplantation (medical source OR: 8,7 [2,8 - 26,7] and no medical source: OR = 6,0 [2,8 - 13,0]) and the knowledge of post-donation follow-up (No follow-up: OR = 0,4 [0,2 - 0,8]) were statistically associated with acceptance of the principle of living kidney donation. Source of information about kidney transplantation (medical source: OR = 6,2 [2,9 - 13,2] and no medical source: OR = 3,0 [1,6 - 5,6]), relationship (parents to children: OR = 3,1 [1,1 - 8,6]) and parent's financial dependence on the hemodialysis patient (OR = 2 ,7 [1,27-5,72]), were statistically associated with willingness to donate kidney.

Conclusions

Relatives of hemodialysis patients accept the principle of living kidney donation and are willing to donate a kidney to their relative.

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