COMPARISON OF HANDHELD VERSUS HIGH-END ULTRASOUND DEVICES FOR THE GUIDANCE OF PERCUTANEOUS KIDNEY BIOPSY

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COMPARISON OF HANDHELD VERSUS HIGH-END ULTRASOUND DEVICES FOR THE GUIDANCE OF PERCUTANEOUS KIDNEY BIOPSY
Cristina
Chediak
Adela Anguisaca crischediak@hotmail.com Hospital General Docente de Calderon Nephrology Quito
Lilian Mendieta crischediak@yahoo.com Hospital General Docente de Calderon Nephrology Quito
Mayra Oñate crischediak@hotmail.com Hospital General Docente de Calderon Nephrology Quito
Belen Larco crischediak@gmail.com Hospital General Docente de Calderon Nephrology Quito
Meri Orna drachediak@gmail.com Hospital General Docente de Calderon Nephrology Quito
 
 
 
 
 
 
 
 
 
 

Kidney biopsy is the most vital tool guiding a nephrologist in diagnosis and treatment of kidney diseases. The goal of our study was to compare the adequacy and complication rates between kidney biopsies performed by nephrologists using mobile handheld (HH-US) in contrast to high-end ultrasound devices (HE-US).

Retrospective study of all ultrasound (US) guided native kidney biopsies performed by nephrologists at a secondary Hospital between 2021 and 2023. The US devices used included the Butterfly iQ device connected to an iPhone and the Phillips Sparq Ultrasound System (picture 1).

Fifty-seven native kidney biopsies were performed in the study period, of which 22 (38.9%) were performed with HH-US and 35 (61.4%) with HS-US.

 

Of all patients, 56.1% % (n=32) were females and the mean age was 33,8 ± 12.7 years. The most frequent comorbidity was systemic lupus erythematosus (38,6%, n=22) followed by arterial hypertension (21,1%, n=12) and the most common indication for kidney biopsy was nephrotic syndrome (43,9%, n=25) followed by lupus with active urine sediment (38,6%, n=22) (Table 1).

 

The biopsy samples were almost always taken from the left side (96,5% n=55), with a needle gauge of 16 G (91,2% n=52). The needles were used for a median of 2,2 passes (± 0,5) and collected a median of 15,7 ± 8.1 glomeruli for optical microscopy. Primary glomerular disease (PGD) was reported in 52,7% (n=30), while secondary glomerular disease was reported in 44% (n=25) of the biopsies studied. (Table 2).

 

There were no complications in 82.5% (47 biopsies), minor complications in 17,5% (10 biopsies) and no major complications of the procedures. The most frequent minor complications were pain lasting ≥ 12 hours (7%, n=4), hematoma (7%, n=4) and gross hematuria (3,5%, n=2).

 

No significant differences in post-biopsy complications such as pain, hematoma, need for transfusion and intervention, gross hematuria or infection were observed between HH-US and HE-US. (no complication in 82,5% HH-US vs 72,7% HS-US, p = 0.39)

 

The overall adequacy rate of native biopsy was 85,7% (n= 48), with no significant difference among groups (81,8% HH-US vs 88,2% HS-US, p = 0.5).


Our results suggest that there is no significant difference in the adequacy or complication rates between kidney biopsies performed with HH-US and HS-US.

The use of portable US devices for the guidance of percutaneous renal biopsy could be a low-cost, efficient and safety alternative to high- end US devices in low- and middle-income countries, depending on each institution’s resources and expertise.

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