Risk factors of CKD incidence in Korea NHIS data : Focusing on the influence of diabetes

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Abstract Title

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Ki Ryang

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Co-author 1

Dae Eun Choi daenii@cnu.ac.kr Chungnam National University Medical Science Daejeon

Co-author 2

Hyerim Park hye05240@gmail.com Chungnam National University Hospital Medical Science Daejeon

Co-author 3

Young Rok Ham youngrok01@cnuh.co.kr Chungnam National University Hospital Nephrology Daejeon

Co-author 4

Eu Jin Lee eujinlee@cnuh.co.kr Chungnam National University Hospital Nephrology Daejeon

Co-author 5

Kyungho Park ds3ixd@gmail.com Chungnam National University Hospital Nephrology Daejeon

Co-author 6

Yoon-Kyung Chang racer@catholic.ac.kr Daejeon Saint Mary Hospital Nephrology Daejeon

Co-author 7

Moo Jun Kim kimmoojun@cnuh.co.kr Chungnam National University Sejong Hospital Nephrology Sejong

Co-author 8

Hae Ri Kim yo0118@cnuh.co.kr Chungnam National University Sejong Hospital Nephrology Sejong

Co-author 9

Co-author 10

Co-author 11

Co-author 12

Co-author 13

Co-author 14

Co-author 15

Introduction

The global prevalence of CKD continues to increase, with diabetes accounting for the highest proportion. There is a lack of information on how much diabetes will affect the incidence of CKD in the eGFR group measured in the single examination.

Methods

The Sample Cohorts Database provided by the National Health Insurance Sharing Service (NHISS) in Korea was used. Participants aged 40 years or older (n=148,089) who underwent a health check-up in 2009 were stratified into 6 groups according to eGFR measurement values and diabetes presence. Participants in each group were tracked from 2010 to December 31, 2019. The CKD incidence rate in each group and the effect of accompanying factors on CKD incidence were confirmed.

Results

In the same eGFR group, the incidence of CKD was higher than in the group without diabetes. The CKD incidence rates were similar between the eGFR < 60 group and the eGFR 60-90 group with diabetes. The CKD incidence rate was higher in the eGFR > 90 group with diabetes than the eGFR 60-90 group without diabetes. Older age, current smoker, men, hypertension, dyslipidemia, myocardial infarction history, and atrial fibrillation and flutter increased the risk of CKD.

Conclusions

The incidence of CKD depends on the level of eGFR and comorbidity, including diabetes. Accordingly, appropriate monitoring and management are required.

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