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Peritoneal dialysis is an effective renal replacement therapy that offers a longer preservation of the residual renal function, a better blood pressure regulation and quality of life. The use of diuretics is safe and beneficial but sometimes ineffective.
With this meta-analysis, was investigated the possible beneficial role of tolvaptan in the body fluid control and the management of heart failure markers (LVMI, BNP) in individuals undergoing peritoneal dialysis.
Tolvaptan as an adjuvant therapy appears to be useful on the volume control and potentially improve the cardiac function. More high-quality studies are required.