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Acute kidney injury is common and affects approximately 5% to 10% of hospitalized patients and up to 60% of patients admitted to the intensive care unit (ICU). Acute kidney injury has a variety of causes and should not be viewed as a single disease.
Patients requiring renal replacement therapy (KDIGO 3) are patients with previous normal renal function and risk factors or with multiple comorbidities, who require immediate renal replacement therapy with close follow-up during hospitalization to assess whether they have partial or complete recovery of renal function.
Research Question What are the factors associated with partial or full recovery in hospitalized patients with KDIGO III acute kidney injury at ISSEMyM Medical Center who required renal function replacement therapy in the period 2020 - 2023?
Primary Objective
To determine which factors are associated with partial or total recovery of renal function in hospitalized patients with acute kidney injury KDIGO 3.
An observational, retrospective, longitudinal, longitudinal, clinical and analytical study was carried out at the Centro Medico ISSEMyM Toluca in 57 hospitalized patients with acute kidney injury KDIGO 3 who required renal function replacement therapy in the period 2020-2023.
Statistical analysis: The Shapiro Wilk or Kolmogorov Smirnov test was applied to quantitative variables, as appropriate, and a p-value of less than 0.05 was considered statistically significant. Mean and standard deviation and median with interquartile ranges with 25th and 75th percentile were used to show variables with normal or free distribution, respectively. Qualitative variables are shown with frequencies and percentages.
Inferential analysis. The information was grouped according to two grouping criteria: 1.- Parameters at the beginning of RRT and parameters at the time of withdrawal of RRT 2.- Patients who had partial or total recovery to RRT and patients who did not have recovery to RRT
Baseline characteristics at the beginning of the study (table 1).
Within the series that exist at the moment, our study was similar in terms of sex predominantly male, age, on average 60 years, Diabetes Mellitus as the main comorbidity. In the inferential analysis, the recognition of hyperkalemia in acute kidney injury allows an early intervention with consequent recovery. Previous chronic renal disease is a factor against the recovery of renal function to its baseline. Early detection of acute kidney injury allows interventions that change the natural course of the disease, favoring the withdrawal of replacement therapy, lower costs and better evolution.