PERFORMANCE AND OUTCOME OF PIONEERING KIDNEY TRANSPLANTATION IN A RESOURCE-CONSTRAINED SETTING IN SOUTHEAST NIGERIA

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https://storage.unitedwebnetwork.com/files/1099/80875c242593de65daf53a1b09da8d76.pdf

Abstract Title

First Name *

Chimezie

Last Name *

Okwuonu

Co-author 1

George Achor achorgo@yahoo.com Federal Medical Center Urology, Surgery Umuahia Abia State

Co-author 2

Nosike Erondu erondunosike@yahoo.com Federal Medical Centre Anesthesia Umuahia, Abia State

Co-author 3

Paul Ngwu paulngwu66@gmail.com Federal Medical Centre Urology, Surgery Umuahia, Abia State

Co-author 4

Sani Alhassan smaakh@yahoo.com Aminu Kano Teaching hospital Urology, Surgery Kano

Co-author 5

Obi Ekwenna obinna.ekwenna@utoledo.edu University of Toledo Medical Center Transplant, Urology Toledo, Ohio

Co-author 6

Chuku Abali chukuabali@yahoo.com Federal Medical Centre Ophthalmology Umuahia, Abia State

Co-author 7

Ijezie Chukwuonye chukwuonye4@yahoo.com Federal Medical Centre Nephrology, Internal Medicine Umuahia, Abia State

Co-author 8

Ego Okam udookam@gmail.com Federal Medical Centre Nursing Services Umuahia, Abia State

Co-author 9

Azubuike Onyebuchi kanayo009@yahoo.com Federal Medical Centre Obstetrics/Gynaecology Umuahia Abia State

Co-author 10

Rasheed Balogun rb8mh@uvahealth.org University of Virginia Health Nephrology, Internal Medicine Charllottesville, Virginia

Co-author 11

Co-author 12

Co-author 13

Co-author 14

Co-author 15

Introduction

Kidney transplantation is the optimal treatment for improving survival and quality of life for patients with end-stage kidney disease. Kidney transplantation is developing in Nigeria. There was no kidney transplant surgery and acute care services in Southeast Nigeria until 2017 when our institution commenced such services. The objectives of this study to obtain the transplant conversion rate, short and long term complications and the graft and patient survival over a six year period.

Methods

A retrospective cohort review of the transplant register for patients referred to the kidney transplant unit from January 2017 to December 2022. The socio-demographic data, duration on dialysis, aetiology of kidney disease, laboratory investigations, number of patient transplanted, acute complications and outcome of the transplantation were obtained.

Results

Conclusions

The transplant conversion rate was low. Assisted funding of kidney transplant activities by government and non-governmental agencies, and a periodic review of other barriers to transplant will improve access to kidney transplantation in Nigeria. Acute complications were treatable in most cases. The patient and graft outcomes appear similar to reults obtained from other centres in Nigeria but our five year survival differs from that of developed countries.

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