FREQUENCY OF CHRONIC KIDNEY DISEASE IN AN AREA OF HIGH INCIDENCE OF TERMINAL CHRONIC KIDNEY DISEASE AND ITS ASSOCIATED RISK FACTORS

E-Poster

https://storage.unitedwebnetwork.com/files/1099/9a3799641b68d14f0e514faa512e3f6f.pdf

Abstract Title

First Name *

Hugo E.

Last Name *

Chavez Chavez

Co-author 1

Darío Oseguera Herrera darioseguerah@gmail.com Autonomous University of Guadalajara Medicine Guadalajara

Co-author 2

Valeria Contreras Oseguera vale40199@gmail.com Autonomous University of Guadalajara Medicine Guadalajara

Co-author 3

Ma de Lourdes. Ochoa Campollo lourdes.ochoacampollo@gmail.com Autonomous University of Guadalajara Medicine Guadalajara

Co-author 4

Lucio O. Sanchez Macías lucioosm@gmail.com Hospital San Javier Nephrology Guadalajara

Co-author 5

Alfonso M. Cueto Manzano a_cueto_manzano@hotmail.com Specialty Hospital National Medical Center of the West Renal research unit guadalajara

Co-author 6

Fabiola Martín-del-Campo fabiola.martindelcampo@academicos.udg.mx Specialty Hospital National Medical Center of the West Renal research unit Guadalajara

Co-author 7

Co-author 8

Co-author 9

Co-author 10

Co-author 11

Co-author 12

Co-author 13

Co-author 14

Co-author 15

Introduction

Jalisco is one of the states of Mexico with the highest incidence and prevalence of end-stage chronic kidney disease (ESKD). Poncitlán is one of the most affected regions, but the prevalence of chronic kidney disease (CKD) and its risk factors have not yet been fully elucidated

Methods

To describe the frequency of CKD by stage, and its associated risk factors, in relatives of patients with CKD in the region of Poncitlán, Chapala, Jalisco. We perform a cross-sectional study. In a community help center where the state government cares for families at high risk of ESKD. 305 family members of patients with ESKD were invited to participate in this study. For those who accepted, a medical history was taken and exposure to environmental and nutritional factors, as well as family history and anthropometry, were evaluated. The serum creatinine concentration was determined to estimate the glomerular filtration rate (GFR) by CKD-EPI formula, as well as albumin to creatinine ratio in one spot urinary sample.

Results

890 subjects were evaluated, 632 (71%) women and 258 (29%) men, 438 pediatric and 452 adults; only 608 people took the urine test (68%) and 618 the blood test (69%). Considering adult subjects with renal function evaluation: 62 (20.7%) had albuminuria, 19 (6.1%) had a GFR <60 ml/min/1.73m2. With the combined data of GFR and albuminuria, 68 (23.4%) had CKD (See Table). The associated factors in adults were: older age, higher medication consumption, history of hyperuricemia, dyslipidemia, chronic kidney disease, systemic arterial hypertension, diabetes mellitus, and higher blood pressure and body mass index. In the family analysis, those families in which a member presented CKD more frequently live on the shore of the lake or near a farming area.

Conclusions

In this sample of relatives of patients with ESKD, the frequency of ESKD seems higher than that reported in the literature, and the risk factors were similar to those traditionally reported in adult patients. Interestingly, families with positive CKD cases live more frequently on the shore of the lake or near a farming area.

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