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Glomerulonephritis is a group of diseases characterized by glomerular damage, commonly immune-mediated, with risk of progression to chronic kidney disease. The kidney biopsy is the gold standard for diagnosing. In Mexico there is 1 report until 2012 of 423 kidney biopsies while in the USA a study reported 4128 biopsies in 6 years. More records are needed to know the clinical and epidemiological characteristics of the patients.
The aim of this study was clinical and histopathological characterization of glomerular diseases in a hospital in southeastern Mexico from March 2022 to July 2023. A descriptive, observational and prospective study was carried out, included: age, sex, clinical presentation, baseline creatinine, baseline glomerular filtration rate (GFR) by CKD-EPI equation, creatinine clearance (CrCl) from 24-hour urine collection, proteinuria, histopathological diagnosis and renal function at 6 months. All were performed ultrasound-guided by a nephrologist with trans-procedural confirmation of optimal sampling by a nephropathologist.
The present study represents the 1st registry in our hospital, due to social and economic difficulties that for a long time have prevented their performance and registration. The most frequent clinical manifestation was edema and the clinical syndrome on admission was hematuria-proteinuria. Lupus nephritis was the most frequent histopathological diagnosis.