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Bone mineral disorder - conical renal disease is a syndrome that includes one or more alterations of: calcium, phosphorus, parathormone, vitamin D; remodeling, bone mineralization or volume, vascular or soft tissue calcifications. Generating high cardiovascular risk and fractures. Objective: To determine the prevalence of bone mineral disorder - chronic kidney disease in hemodialysis patients in a reference center
Descriptive and association study, observational, cross-sectional, prolective, which included patients with chronic kidney disease on hemodialysis older than 18 years who agreed to participate. Sample size for prevalence of 60%, with alpha probability of 0.05 and precision factor of 0.1 was 93 patients, however, only 27 patients agreed to participate. Serum values of PTH, calcium, phosphorus, calcidiol, time on hemodialysis, age, sex, and presence of diabetes were obtained. Data processing analyzed with SPSS 22, ORP calculation with 95% CI, Chi square and logistic regression p<0.05.
90% prevalence of bone mineral disorder, prevalence of high turnover bone disease 81.2%. The association of vascular calcifications with age OR 1.324 IC (1.003 to 1.7) p 0.04, with PTH OR 1.001 IC (0.9 to 1.04) p 0.3 and with time on hemodialysis 3.4 (0.2-46.4) p 0.04
In our population, the prevalence of bone mineral disorder is consistent with that reported in the literature. Our patients present a high frequency of vascular calcifications and a predominance of high turnover bone disease. The underdiagnosis of this disorder generates complications that have an impact on cardiovascular morbidity and mortality.