INCIDENCE OF ACUTE KIDNEY INJURY AND THE NEED FOR RENAL SUPPORT THERAPY IN THE POSTOPERATIVE PERIOD OF CARDIOVASCULAR SURGERY

E-Poster

https://storage.unitedwebnetwork.com/files/184/3e293ce2802e36e591c3656dabecfd34.pdf

Abstract Title

First Name *

Henry Joseth

Last Name *

González-Torres

Co-author 1

Daniel Ospina Herrera daniel.ospina@unisimon.edu.co Universidad Simón Bolívar Facultad de Ciencias de la Salud Barranquilla

Co-author 2

Gustavo José Aroca Martínez gustavo.aroca@unisimon.edu.co Universidad Simón Bolívar Facultad de Ciencias de la Salud Barranquilla

Co-author 3

Adriana Isabel Agamez Diaz aagamez5@unisimon.edu.co Universidad Simón Bolívar Facultad de Ciencias de la Salud Barranquilla

Co-author 4

Sofia Aguilera Caro daney.aguilera@unisimon.edu.co Universidad Simón Bolívar Facultad de Ciencias de la Salud Barranquilla

Co-author 5

Alex Alfredo Dominguez Vargas dominguezaa@uninorte.edu.co Universidad del Norte Division Ciencias de la Salud Barranquilla

Co-author 6

Co-author 7

Co-author 8

Co-author 9

Co-author 10

Co-author 11

Co-author 12

Co-author 13

Co-author 14

Co-author 15

Introduction

Major surgery is the second leading cause of Acute Kidney Injury (AKI), with cardiovascular surgery having the highest incidence. This is due to technical conditions like aortic clamping and extracorporeal circulation, which lead to systemic reactions including embolism formation, low cardiac output, prolonged hypotension, and contact-activated systemic inflammation. This study aimed to evaluate the incidence of AKI and the need for renal support therapy after cardiovascular surgery.

Methods

A cross-sectional study was conducted, involving statistical summaries and Wilcoxon test for median comparison in quantitative data. Fisher's exact test or Chi-squared test were used for qualitative data. Multivariate logistic regression analysis was performed, adjusted by the "Backward" method, to identify potential mortality-associated factors, reporting ORs, 95% CIs, and p-values for each variable. A p-value < 0.05 was considered statistically significant. R-CRAN software version 4.3.2 was used for statistical analysis.

Results

This study examined 137 patients undergoing cardiovascular surgery, mostly male (75%), with a median age of 62. Common comorbidities included hypertension (60%), type 2 diabetes (17%), acute kidney injury (15%), and non-dialytic chronic kidney disease (12%). 11% died during the study. Patients with acute kidney injury (LRA) had higher prevalence of type 2 diabetes compared to those without (35% vs. 14%). Non-dialytic chronic kidney disease prevalence in LRA patients was 30%. Bentall surgery was more common in LRA patients (20% vs. 5.1%). LRA patients underwent extracorporeal circulation more often (80% vs. 52%). LRA presence correlated with higher mortality risk (OR: 7.14, p = 0.006). BCEC use during surgery also raised mortality risk (OR: 6.86, p = 0.030).

Conclusions

In patients undergoing cardiovascular surgery, hypertension was the most common comorbidity (60%). Acute Kidney Injury (AKI) was prevalent, particularly in those with diabetes (35%). AKI and the use of extracorporeal circulation were associated with higher postoperative mortality risk.

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