OUTCOMES OF LIVE RELATED RENAL TRANSPLANT RECIPIENTS WITH THE USAGE OF ATLG VS BASILIXIMAB AS AN INDUCTION AGENT

Back

E-Poster

https://storage.unitedwebnetwork.com/files/1099/a719cffeb2198e847aa4b487040f437b.pdf

Abstract Title

First Name *

Ruchir

Last Name *

Dave

Co-author 1

Akash Shah drakash0541@gmail.com IKDRC-ITS Nephrology and Transplantation Ahmedabad

Co-author 2

Himanshu Patel drhvpatel@gmail.com IKDRC-ITS Nephrology and Transplantation Ahmedabad

Co-author 3

Vivek Kute drvivekkute@rediffmail.com IKDRC-ITS Nephrology and Transplantation Ahmedabad

Co-author 4

Subho Engineer drsubhobanerjee@gmail.com IKDRC-ITS Nephrology and Transplantation Ahmedabad

Co-author 5

Divyesh Engineer engineerdivyeshp@gmail.com IKDRC-ITS Nephrology and Transplantation Ahmedabad

Co-author 6

Co-author 7

Co-author 8

Co-author 9

Co-author 10

Co-author 11

Co-author 12

Co-author 13

Co-author 14

Co-author 15

Introduction

There are few prospective studies comparing outcomes of anti T-lymphocyte immune globulin (ATLG) and IL-2RB (Basiliximab) in living related kidney transplant recipients (LRTR).

Methods

This was an ethically approved, prospective, observational report with probability-based sampling excluding deceased donor, sensitized, and poor mismatch groups. Primary outcome measured was Biopsy proven acute rejection (BPAR). Secondary outcomes were graft loss, infections and death. Data was analyzed by multi-variable cox hazard analysis, and competing risks by STATA16

Results

Of total 74 LDKT cases, 31 were ATLG and 43 were IL-2RB. The first and last transplant was done on 22 Dec 2020 and 30 Dec 2021 respectively with 1-year follow-up. The median(IQR) age of recipients and donors was 28(24-33) and 52(46-56) years respectively. In cox analysis, there was no difference in terms of BPAR (HR: 0.12, 95% CI: 0.009-1.5, p-value = 0.1) and infections (HR: 0.43 95% CI: 0.12-1.44, p-value = 0.172). However, allograft biopsies were less often performed in IL-2RB compared to ATLG (HR:0.08, 95% CI: 0.01-0.49, p-value =0.006). There was no statistical difference for serum creatinine between two groups at various follow-ups. There was one mortality and graft loss in the study.

Conclusions

Outcomes of ATLG and IL2-RB are comparable in moderate risk LRTR in our study.

E-Poster Format Requirements

PDF file
Layout: Portrait (vertical orientation)
One page only (Dim A4: 210 x 297mm or PPT)
E-Poster can be prepared in PowerPoint (one (1) PowerPoint slide) but must be saved and submitted as PDF file.
File Size: Maximum file size is 2 Megabytes (2 MB)
No hyperlinks, animated images, animations, and slide transitions
Language: English
Include your abstract number
E-posters can include QR codes, tables and photos