Big Data Lab 4 - Link Kidney Genetics and Genomics in Experimental Research: NephQTL

8 Feb 2025 11:15 a.m. 12 p.m.
Big Data Lab

Session description: 
Explore kidney disease genomics with NephQTL, a comprehensive eQTL/CRE portal.   In this session you will uncover how genomic variants regulate specific genes using high-resolution data for precise gene-mapping. 
Learning objectives:
Access eQTLs derived from glomerular and tubulointerstitial samples from the NEPTUNE Nephrotic Syndrome observational study patient cohort.
- Learn how to leverage kidney single-nucleus open chromatin data for enhanced eQTL accuracy. 
- Navigate the interactive search through eQTLs, snATAC-seq tracks, snRNA-seq counts, and single-cell deltaSVM scores. 
- Finally, dive into validated variants and genes demonstrated by the experimental models accessible in the software. 

Click here to sign up for the Big Data Lab Session: https://events.theisn.org/wcn25/book/bdl