RELATIONSHIP OF INTRAABDOMINAL PRESSURE WITH BODY COMPOSITION IN PATIENTS ON PERITONEAL DIALYSIS

8 Feb 2025 12 a.m. 12 a.m.
WCN25-AB-4600, Poster Board= SAT-555

Introduction:

The measurement of intra-abdominal pressure (IAP) in peritoneal dialysis (PD) is a simple and non-invasive procedure. The IAP value should not exceed 18 cm H20, since if this occurs, alterations in peritoneal transport, net ultrafiltration, peritoneal clearance, higher risk of hernias and peritoneal fluid leaks could occur. There are no data relating IAP value with body composition of these patients, except that IAP is higher in patients with greater body surface area.

The aim of this work was to evaluate the relationship of IAP with body composition in patients of the peritoneal dialysis program of Da Vita Chile.

Methods:

Observational study of patients with chronic kidney disease, over 18 years of age, treated during year 2023 in Peritoneal Dialysis Program from Da Vita Chile. Clinical records from the EuCliD electronic record were reviewed, and analysis was carried out using summary statistics, univariate and bivariate analysis. The work had Ethics committee approval from Hospital Clínico Universidad de Chile.

Results:

171 patients distributed throughout the country were studied. 42.7% were male with an average age of 52.8 ± 15.5 years, and average time on PD of 3 years. 40.9% of patients were fast average transporters, followed by 39.8% with slow average transporters. The patients had a Kt/V of 2.2 ± 0.8, a weight of 70.5 ± 15.3 kg, a BMI of 26.7 ± 4.8 kg/m2, a lean tissue index (LTI) of 15.3 ± 4.1 Kg/m2 and fatty tissue index (FTI) of 10.8 ± 6.1 Kg/m2 and ultrafiltration (UF) of 851.5 ± 708.5 ml day.

The average IAP was 16.6 ± 3.8 cm H2O, where 34.0% of patients had IAP ≥ 18 cm H2O.

Patients with IAP ≥ 18 cm H2O compared with IAP < 18 cm H2O, had higher BMI (29,5 ± 4,9 versus 25,4 ± 4,1, p<0,05), higher weight (76,5 ± 4,9 versus 67,7 ± 13,9, p<0,05), and higher FTI (12,9±5,5 versus 9,5 ± 5,4 Kg/m2, p< 0,05). There were no statistically significant differences in age, total Kt/V and LTI between both groups of patients.

Conclusions:

Our data support that peritoneal dialysis patients with IAP ≥ 18 cm H2O have a larger body surface area and higher weight, data already described. It stands out as a novel finding that patients with IAP ≥ 18 cm H2O have a significantly higher fatty tissue index, which could be associated with greater visceral fat that may explains this increase in IAP.

I have no potential conflict of interest to disclose.

I did not use generative AI and AI-assisted technologies in the writing process.