Introduction:
The perioperative period of Kidney Transplantation (KT) is associated with significant changes in fluid and electrolyte status. In the first 48 hours after KT there is often brisk diuresis, large volumes of IV fluids are administered, hyperglycaemia often necessitates insulin therapy & drugs like CNI are known to induce dyselectrolytaemia. An ideal regimen for fluid replacement in the early post KT period is not yet identified; commonly used fluids are NS, 5% Dextrose and RL in varying proportions. We studied the frequency and factors associated with dyselectrolytaemia in the KT recipient in the first 48 hours after transplantation
Methods:
This was a single-centre retrospective case records-based study, which included data of all patients who underwent KT between January 2020 & July 2023. All patients received the institutional protocol for IV fluids. Patients requiring any form of RRT were excluded
Results:
The study includes 82 KT patients with an average age of 31.9 ± 9.37 years at the transplant. 81.7% were male, and 84.1 % were from living kidney donors. The most common cause of CKD was CGN (30.5%), followed by CKDu (25.6%). The average urine output was 12253 (+-5851) on day 0. Hypomagnesaemia (71.4%), hypocalcaemia (79.8%), hyponatraemia (45.2%), hypophosphataemia (22.4%), hypokalaemia (36.6%) & hyperkalaemia (15.9%) were the most encountered abnormalities and most of them persisted at 72 hours. The incidence of hyponatraemia, hypokalaemia, hypophosphataemia, hypocalcaemia and hypomagnesaemia correlated with the urine volume in the first 48 hours and the volume of IVF administered
Conclusions:
Dyselectrolytaemia is very common in the early postoperative period after kidney transplantation and is related to the graft function
I have no potential conflict of interest to disclose.
I did not use generative AI and AI-assisted technologies in the writing process.