THE EFFECT OF A SINGLE SESSION OF INTRADIALYTIC AEROBIC EXERCISE ON FATIGUE , FUNCTIONAL CAPACITY & SOLUTE REMOVAL IN CKDVD - PILOT STUDY

8 Feb 2025 12 a.m. 12 a.m.
WCN25-AB-3754, Poster Board= SAT-235

Introduction:

Haemodialysis of 4 hours/day thrice a week makes patient inactive for that period and fatigue after dialysis can prolong the inactive period at home. Published literature has shown that intradialytic exercise can improve solute removal, dialysis adequacy, intradialytic protein synthesis, muscular strength, peak oxygen consumption, nutritional status, and quality of life.

Aims :

To compare fatigue , functional capacity and solute removal in the experimental and control group.

Study Type : Experimental cross over study

Methods:

30 adult patients CKD VD , on MHD ,for > 3 months were screened. Fatigue was assessed using Fatigue Assessment Scale [FAS ] and Functional Capacity with Six minutes Walk Test [ 6 MWD] performed as per the ATS guidelines before the first session of hemodialysis (Baseline). FAS, 6MWT & Kt/V were assessed after HD in two groups : without intradialytic exercise (Control group) and following intradialytic aerobic exercises (Experimental group). SPSS software version 28 IBM India was used for the analysis.

Results:

The mean 6MWD difference (Control group- Baseline ) was -4.56+/-38.69 and (Experimental Group - Baseline ) was 10.52+/-36 (p= 0.007). The patients in the experimental group walked 15 meters more than the Control group. In the Control group , the mean Kt/V ratio was 1.29+/-0.241 and in the Experimental group the mean Kt/V ratio was 1.37+/-0.2836(p>0.05). A single session of intradialytic exercise increased Kt/V urea ratio by 7%. At Baseline , the median FAS score was 16.5, of control group was 18.00 and of the experimental group was 17.00(p > 0.01).There was no significant increase in fatigue levels in the experimental group. 

Conclusions:

A single session of Intradialytic exercise showed a statistically significant improvement in 6MWD (p = 0.007) and Kt/V ratio (p = 0.031) and a statistically significant reduction in FAS (p=0.016 ).

I have no potential conflict of interest to disclose.

I did not use generative AI and AI-assisted technologies in the writing process.