Introduction:
Glomerular disease is a prevalent kidney disease in Bangladesh. Glomerulonephritis (GN) varies regionally. The lack of registry data makes it unclear which type of GN is prevalent in Bangladesh. Sylhet Division's only tertiary government hospital, Sylhet M A G Osmani Medical College Hospital(SOMCH), serves 12.1 million people. There have been no studies conducted to determine the pattern of GN in Sylhet.
Methods:
We Prospectively recorded data of renal biopsy performed on consecutive GN patients admitted to Nephrology from June 2021 for two years. Adult patients over 18 years with clinical and laboratory characteristics GN were included and all the biopsies and histopathological studies were conducted by same nephrologist and histopathologist. Study samples with fewer than 10 glomeruli were eliminated.
Results:
Total 103 patients were recruited with mean age (31±14.3 years) and female predominant (71.9%). Patients presented with nephrotic syndrome, nephritic syndrome, nephrite-nephrotic presentation, microscopic hematuria ,rapidly progressive GN. The most common histological type of GN was IgA Nephropathy 36.1% followed by Membranoproliferative GN (20.3%), Lupus Nephritis (16.5%), Membranous Nephropathy (7.7%), Focal segmental Glomerulosclerosis (10.6%). However, IgG GN, Adult Minimal Change Disease, C1q Nephropathy, C3 Glomerulonephritis, Pauci Immune GN were observed only in 0.94%-2% of patients. Most common Post biopsy complication was pain (48.5%) followed by Frank Hematuria (16.5%) with zero fatality. However, only two patients required Packed Red Cell transfusion.
Conclusions:
The pattern of glomerular disease in this region of Bangladesh differs from that of other places. It is recommended to establish a national Renal Biopsy registry in Bangladesh in order to gain a more comprehensive understanding of the pattern of GN and to monitor changes in trends over time
I have no potential conflict of interest to disclose.
I did not use generative AI and AI-assisted technologies in the writing process.