Introduction:
INTRODUCTION: Chronic renal impairment represents a major cause of public health worry world-wide with resultant unfavorable effects on other diseases. Renal replacement therapy without any doubt is an integral component in the wholistic care of patients with renal impairment globally with its attendant likelihood for adverse outcomes including intradialytic mortality. Reports on death occurring during dialysis is sparse or non-existent especially in low-income economies including Nigeria hence this study The study will enumerate the prevalence as well as the factors contributing to intra-dialytic mortality in the studied population.
Methods:
METHODS: A retrospective evaluation of the clinical and dialysis records of 188 adult patients who had haemodialysis in the dialysis unit of UniOsun Teaching Hospital Osogbo, over a 3-year period was carried out. A comparison of clinico-demographic parameters was carried out between patients who experienced intra-dialytic mortality and those who had uneventful dialysis sessions. Data was analysed using SPSS version 24.
Results:
RESULTS: During the years under review, 14 (7.4%) of the 188 patients dialysed experienced intradialytic mortality with a mean age of 40.6 ± 16.0 years for those that died. More female died intradialysis compared to their male counterpart (M:F ratio = 1:3.6). Among those that died chronic kidney disease was the commonest diagnosis (n= 8, 57.2%) while acute kidney injury accounted for 32.8% of the diagnosis. Half of the deaths occurred on Friday (50%) and mostly at night (n=8,57.1%). The source of admission for dialysis (P=0.046), female gender (P=0.05), occurrence of intradialytic hypotension (P= 0.001), high predialytic systolic blood pressure (P= 0.039), underlying type of kidney disease (P=0.023), intra-dialytic level of consciousness (P=0.001) as well as dialysis reaction time (P=0.009) were associated with increased likelihood of intra-dialytic death. On multi-variate analysis source of admission (OD=0.000, P-value=0.998), in-patient status at last dialysis (OD=0,000, P-value=0.992), intradialytic hypotension (OD=0.000, P-value=0.980), predialytic systolic blood pressure (OD=25.431, P-value=0.981) and dialysis reaction time (OD=1696, P-value=0.981) were not predictive of mortality.
Conclusions:
CONCLUSION: The occurrence of intradialytic mortality is dependent on predialytic as well as intradialytic factors although none of these factors exhibited predictive ability on multivariate analysis.
I have no potential conflict of interest to disclose.
I did not use generative AI and AI-assisted technologies in the writing process.