Introduction:
Upper Gastrointestinal Bleeding (UGIB) is a common cause of hospital admission in patients with End-Stage Chronic Kidney Disease (ESKD). The presence of multiple comorbidities and a uremic microenvironment increases the risk of complications and mortality in these patients. Despite its prevalence, there is limited information on the predisposing factors and predictive scores for adverse outcomes in this population.
Methods:
Retrospective clinical study at Hospital Civil de Guadalajara, Mexico, from july 21 until April 24, all patients with ESRD admitted to the Nephrology service with UGIB. We analyzed the comorbidities, symptoms, endoscopic finding and evolution during their hospitalization and compared them with HTDA and ESRD prevalent.We performed a statical analysis in SPSS, including frequencies, percentages, mean (SD), median (IQR), Studen´s T test, chi square, fisher or Mann Whitney U to compare between groups
Results:
We analyzed 180 patients, 65% were male, with a mean age of 46 years. Fifty-three percent of the patients does not have previously dialysis therapy.
Only 52% of the patient had diagnosed endoscopy during their hospitalization, the rest were discharged with PPI after the resolution of symptoms and having received dialysis, while awaiting outpatient endoscopy. See table 1-3
Conclusions:
Endoscopic findings most common were ulcers and erosive esophagitis, angiodysplasia was a rare finding. Patients with higher Urea and SCr were managed with dialysis and endoscopy was delayed, this could be because the bleeding was attributed to uremic syndrome and treatment focused on resolving uremia before performing endoscopy. UGIB was part of the symptoms attributed to uremic syndrome in more than 50% of the patients.
I have no potential conflict of interest to disclose.
I did not use generative AI and AI-assisted technologies in the writing process.